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gpDB::G-protein View
Entry 1 of 1 :: GPR0169 ::
CLASS Gbeta
FAMILY Gbeta
SUBFAMILY Gbeta
TYPE Gbeta-5

Cross References:
UniProt P62882 | O35354 | P54314 | Q5FWS8 | Q91WB3 EMBL AF001953 | AY552803 | BC089221 | AF022086
InterPro IPR001632 | IPR015943 | IPR001680
PRODOM PD000018
GENEID 83579
PRINTS PR00319 | PR00320 PFAM PF00400

Details:
NAME Gbeta-5-Rattus norvegicus
DESCRIPTION Guanine nucleotide-binding protein subunit beta-5 (Transducin betachain 5) (Gbeta5).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
POST TRANSLATION MODIFICATIONS null GENE Gnb5
SEQUENCE 
MATDGLHENETLASLKSEAESLKGKLEEERAKLHDVELHQVAERVEALGQFVMKTRRTLK
GHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAI
ACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALW
DVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHES
DVNSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFA
GYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Effectors:
1EFF0011Adenylate cyclase-2-Rattus norvegicusStimulation15251227 | 15922020 | 14993377 | 11376933
2EFF0026Adenylate cyclase-4-Rattus norvegicus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
3EFF0027Adenylate cyclase-4-Rattus norvegicus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
4EFF0036Adenylate cyclase-5-Rattus norvegicusInhibition15251227 | 15922020 | 14993377 | 11376933
5EFF0042Adenylate cyclase-6-Rattus norvegicusInhibition15251227 | 15922020 | 14993377 | 11376933
6EFF0052Adenylate cyclase-7-Rattus norvegicus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
7EFF0053Adenylate cyclase-7-Rattus norvegicus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
8EFF0069ATP-sensitive inward rectifier potassium channel-1-Rattus norvegicusStimulation15251227 | 10990455
9EFF0079ATP-sensitive inward rectifier potassium channel-10-Rattus norvegicusStimulation15251227 | 10990455
10EFF0086ATP-sensitive inward rectifier potassium channel-11-Rattus norvegicusStimulation15251227 | 10990455
11EFF0094ATP-sensitive inward rectifier potassium channel-12-Rattus norvegicusStimulation15251227 | 10990455
12EFF0099ATP-sensitive inward rectifier potassium channel-14-Rattus norvegicusStimulation15251227 | 10990455
13EFF0107ATP-sensitive inward rectifier potassium channel-15-Rattus norvegicusStimulation15251227 | 10990455
14EFF0112ATP-sensitive inward rectifier potassium channel-8-Rattus norvegicus-1Stimulation15251227 | 10990455
15EFF0113ATP-sensitive inward rectifier potassium channel-8-Rattus norvegicus-2Stimulation15251227 | 10990455
16EFF0128Burton's tyrosine kinase-Rattus norvegicusStimulation15251227 | 11698416
17EFF0262Calmodulin-Rattus norvegicus-1Inhibition of calmodulin kinase15251227
18EFF0263Calmodulin-Rattus norvegicus-2Inhibition of calmodulin kinase15251227
19EFF0315Dynamin-1-Rattus norvegicus-1Increased GTPase activity15251227 | 14671004
20EFF0316Dynamin-1-Rattus norvegicus-2Increased GTPase activity15251227 | 14671004
21EFF0356GRK2-Rattus norvegicusRecruitment to plasma membrane15251227 | 14654303
22EFF0364GRK3-Rattus norvegicusRecruitment to plasma membrane15251227 | 14654303
23EFF0403Kir 3.1(GIRK1)-Rattus norvegicus-1Stimulation by beta1-4-containing dimers and inhibition by beta5-containing dimers15251227 | 10944236 | 12661754
24EFF0404Kir 3.1(GIRK1)-Rattus norvegicus-2Stimulation by beta1-4-containing dimers and inhibition by beta5-containing dimers15251227 | 10944236 | 12661754
25EFF0405Kir 3.1(GIRK1)-Rattus norvegicus-3Stimulation by beta1-4-containing dimers and inhibition by beta5-containing dimers15251227 | 10944236 | 12661754
26EFF0416Kir 3.2(GIRK2)-Rattus norvegicus-1Stimulation by beta1-4-containing dimers and inhibition by beta5-containing dimers15251227 | 10944236 | 12661754
27EFF0417Kir 3.2(GIRK2)-Rattus norvegicus-2Stimulation by beta1-4-containing dimers and inhibition by beta5-containing dimers15251227 | 10944236 | 12661754
28EFF0418Kir 3.2(GIRK2)-Rattus norvegicus-3Stimulation by beta1-4-containing dimers and inhibition by beta5-containing dimers15251227 | 10944236 | 12661754
29EFF0419Kir 3.2(GIRK2)-Rattus norvegicus-4Stimulation by beta1-4-containing dimers and inhibition by beta5-containing dimers15251227 | 10944236 | 12661754
30EFF0423Kir 3.3(GIRK3)-Rattus norvegicusStimulation by beta1-4-containing dimers and inhibition by beta5-containing dimers14963032 | 11779482 | 12661754
31EFF0431Kir 3.4(GIRK4)-Rattus norvegicusStimulation by beta1-4-containing dimers and inhibition by beta5-containing dimers15251227 | 10944236 | 12661754
32EFF0528Phospholipase C beta-1-Rattus norvegicusStimulation15251227 | 11015615 | 8383116
33EFF0538Phospholipase C beta-2-Rattus norvegicus-1Stimulation15251227 | 11015615 | 8383116
34EFF0539Phospholipase C beta-2-Rattus norvegicus-2Stimulation15251227 | 11015615 | 8383116
35EFF0552Phospholipase C beta-3-Rattus norvegicus-1Stimulation15251227 | 11015615 | 8383116
36EFF0553Phospholipase C beta-3-Rattus norvegicus-2Stimulation15251227 | 11015615 | 8383116
37EFF0574PI3K alpha-Rattus norvegicus-1Propable Inhibition16182515
38EFF0575PI3K alpha-Rattus norvegicus-2Propable Inhibition16182515
39EFF0584PI3K beta-Rattus norvegicusActivation9305878 | 12502714
40EFF0667Rac-Rattus norvegicus-1Stimulation,Recruitment to plasma membrane11099498 | 15251227
41EFF0668Rac-Rattus norvegicus-2Stimulation,Recruitment to plasma membrane11099498 | 15251227
42EFF0669Rac-Rattus norvegicus-3Stimulation,Recruitment to plasma membrane11099498 | 15251227
43EFF0690Raf1 protein kinase-Rattus norvegicusSequestration of Gβγ15251227
44EFF0703Ras specific nucleotide exchange factor CDC25-Rattus norvegicus-1Stimulation (indirect activation of ras)15251227 | 8717044
45EFF0704Ras specific nucleotide exchange factor CDC25-Rattus norvegicus-2Stimulation (indirect activation of ras)15251227 | 8717044
46EFF0796Rho-Rattus norvegicus-1Recruitment to plasma membrane15251227
47EFF0797Rho-Rattus norvegicus-2Recruitment to plasma membrane15251227
48EFF0798Rho-Rattus norvegicus-3Recruitment to plasma membrane15251227
49EFF0799Rho-Rattus norvegicus-4Recruitment to plasma membrane15251227
50EFF0800Rho-Rattus norvegicus-5Recruitment to plasma membrane15251227
51EFF0801Rho-Rattus norvegicus-6Recruitment to plasma membrane15251227
52EFF0802Rho-Rattus norvegicus-7Recruitment to plasma membrane15251227
53EFF0803Rho-Rattus norvegicus-8Recruitment to plasma membrane15251227
54EFF0804Rho-Rattus norvegicus-9Recruitment to plasma membrane15251227
55EFF0832SHC transforming protein-1-Rattus norvegicus-1Stimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
56EFF0833SHC transforming protein-1-Rattus norvegicus-2Stimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
57EFF0845SHC transforming protein-3-Rattus norvegicusStimulation(indirect activation of MAPK)15251227 | 14671004 | 7568118
58EFF1336Tubulin-Rattus norvegicus-10Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
59EFF1337Tubulin-Rattus norvegicus-11Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
60EFF1338Tubulin-Rattus norvegicus-12Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
61EFF1339Tubulin-Rattus norvegicus-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
62EFF1340Tubulin-Rattus norvegicus-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
63EFF1342Tubulin-Rattus norvegicus-3Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
64EFF1343Tubulin-Rattus norvegicus-4Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
65EFF1344Tubulin-Rattus norvegicus-5Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
66EFF1345Tubulin-Rattus norvegicus-6Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
67EFF1346Tubulin-Rattus norvegicus-7Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
68EFF1347Tubulin-Rattus norvegicus-8Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
69EFF1348Tubulin-Rattus norvegicus-9Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
70EFF1463Voltage dependent N type calcium channel-Rattus norvegicus-1Inhibition15251227 | 11031246
71EFF1464Voltage dependent N type calcium channel-Rattus norvegicus-2Inhibition15251227 | 11031246
72EFF1465Voltage dependent N type calcium channel-Rattus norvegicus-3Inhibition15251227 | 11031246
73EFF1466Voltage dependent N type calcium channel-Rattus norvegicus-4Inhibition15251227 | 11031246
74EFF1489Voltage dependent P/Q type calcium channel-Rattus norvegicus-1Inhibition15251227 | 11031246
75EFF1490Voltage dependent P/Q type calcium channel-Rattus norvegicus-2Inhibition15251227 | 11031246
76EFF1491Voltage dependent P/Q type calcium channel-Rattus norvegicus-3Inhibition15251227 | 11031246
77EFF1492Voltage dependent P/Q type calcium channel-Rattus norvegicus-4Inhibition15251227 | 11031246
78EFF1493Voltage dependent P/Q type calcium channel-Rattus norvegicus-5Inhibition15251227 | 11031246
79EFF1494Voltage dependent P/Q type calcium channel-Rattus norvegicus-6Inhibition15251227 | 11031246
80EFF1495Voltage dependent P/Q type calcium channel-Rattus norvegicus-7Inhibition15251227 | 11031246
81EFF1496Voltage dependent P/Q type calcium channel-Rattus norvegicus-8Inhibition15251227 | 11031246
82EFF1508Voltage dependent R type calcium channel-Rattus norvegicus-1Inhibition15251227 | 11031246
83EFF1509Voltage dependent R type calcium channel-Rattus norvegicus-2Inhibition15251227 | 11031246
84EFF1510Voltage dependent R type calcium channel-Rattus norvegicus-3Inhibition15251227 | 11031246

Coupling with GPCRs:
No information



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