gpDB: a database of G-proteins and their interaction with GPCRs
Introduction Navigation Text Search Blast Search Pattern Search User Manual

gpDB::Effector View
Entry 1 of 1 :: EFF0011 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 2

Cross References:
UniProt P26769 EMBL M80550
InterPro IPR001054 | IPR009398 PDB 1AB8 | 1AZS | 1CJK | 1CJT | 1CJU | 1CJV | 1CS4 | 1CUL | 1TL7 | 1U0H | 2GVD | 2GVZ
GENEID 81636
PFAM PF06327 | PF00211

Details:
NAME Adenylate cyclase-2-Rattus norvegicus
DESCRIPTION Adenylate cyclase type 2 (EC 4.6.1.1) (Adenylate cyclase type II) (ATPpyrophosphate-lyase 2) (Adenylyl cyclase 2).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Adcy2
SEQUENCE 
MRRRRYLRDRAEAAAAAAAGGGEGLQRSRDWLYESYYCMSQQHPLIVFLLLIVMGACLAL
LAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRVFSLVIWICLVAMG
YLFMCFGGTVSAWDQVSFFLFIIFVVYTMLPFNMRDAIIASILTSSSHTIVLSVYLSATP
GAKEHLFWQILANVIIFICGNLAGAYHKHLMELALQQTYRDTCNCIKSRIKLEFEKRQQE
RLLLSLLPAHIAMEM
 FRAGMENT NO
FUNCTION This is a membrane-bound, calmodulin-insensitives adenylyl cyclase
Interacting with G-proteins:
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0124Galpha-s-Rattus norvegicus-2
2GPR0392Galpha-s-Rattus norvegicus-1
Family:Gbeta REFERENCES:15251227 | 15922020 | 14993377 | 11376933
3GPR0149Gbeta-1-Rattus norvegicus-2
4GPR0157Gbeta-2-Rattus norvegicus-2
5GPR0162Gbeta-3-Rattus norvegicus
6GPR0166Gbeta-4-Rattus norvegicus
7GPR0169Gbeta-5-Rattus norvegicus
8GPR0396Gbeta-2-Rattus norvegicus-1
9GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:15251227 | 15922020 | 14993377 | 11376933
10GPR0190Ggamma-5-Rattus norvegicus
11GPR0194Ggamma-7-Rattus norvegicus
12GPR0197Ggamma-8-Rattus norvegicus
13GPR0201Ggamma-11-Rattus norvegicus
14GPR0256Ggamma-2-Rattus norvegicus
15GPR0257Ggamma-3-Rattus norvegicus
16GPR0258Ggamma-4-Rattus norvegicus
17GPR0259Ggamma-10-Rattus norvegicus
18GPR0260Ggamma-12-Rattus norvegicus

Designed for viewing with Internet Explorer 4 or above, Netscape 6 or above.
contact biodbbiol.uoa.gr
for comments, corrections and
data (sequence) submission.
athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory