gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0845 ::
FAMILY SHC transforming proteins
SUBFAMILY SHC transforming proteins
TYPE SHC transforming protein 3

Cross References:
UniProt O70143 EMBL AB001453 | AB001453
InterPro IPR011993 | IPR006019 | IPR006020 | IPR000980
PRODOM PD000093
PRINTS PR00401 | PR00629 PFAM PF00640 | PF00017

Details:
NAME SHC transforming protein-3-Rattus norvegicus
DESCRIPTION SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Shc3 | Nshc | Shcc
SEQUENCE 
MLPRTKYNRFRNDSVTSVDDLLHSLSVSGSGGKVSAEPAASPYLVSGEALRKAPDDGPGS
LGHLLHKVSHLKLSSSGLRGLSSAARERAGARLSGSCSAPSLAAPDGGSATPGSRAPAAS
MSATRKSRASDEPLPRPPRGAPHASDQVLGSGVTYVVKYLGCIEVLRSMRSLDFSTRTQV
TREAISRVCEAVPGAKGAFKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPD
SKQIISNHHMRSISF
 FRAGMENT NO
FUNCTION Signaling adapter that couples activated growth factors receptors to signaling pathway in neurons
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 14671004 | 7568118
1GPR0149Gbeta-1-Rattus norvegicus-2
2GPR0157Gbeta-2-Rattus norvegicus-2
3GPR0162Gbeta-3-Rattus norvegicus
4GPR0166Gbeta-4-Rattus norvegicus
5GPR0169Gbeta-5-Rattus norvegicus
6GPR0396Gbeta-2-Rattus norvegicus-1
7GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:15251227 | 14671004 | 7568118
8GPR0190Ggamma-5-Rattus norvegicus
9GPR0194Ggamma-7-Rattus norvegicus
10GPR0197Ggamma-8-Rattus norvegicus
11GPR0201Ggamma-11-Rattus norvegicus
12GPR0256Ggamma-2-Rattus norvegicus
13GPR0257Ggamma-3-Rattus norvegicus
14GPR0258Ggamma-4-Rattus norvegicus
15GPR0259Ggamma-10-Rattus norvegicus
16GPR0260Ggamma-12-Rattus norvegicus

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