gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF1509 ::
FAMILY Ion channels
SUBFAMILY Voltage dependent calcium channels
TYPE Voltage dependent R type calcium channel

Cross References:
UniProt Q07652 EMBL L15453
InterPro IPR002048 | IPR005821 | IPR014873 | IPR005449 | IPR002077
PRINTS PR00167 | PR01633 PFAM PF08763 | PF00520

Details:
NAME Voltage dependent R type calcium channel-Rattus norvegicus-2
DESCRIPTION Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage-gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type,alpha-1 polypeptide, isoform 6) (RBE-II) (RBE2) (Brain calcium channelII) (BII).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Cacna1e | Cach6 | Cacnl1a6
SEQUENCE
MALYNPIPVRQNCFTVNRSLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALE
QHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVL
SGILATAGTHFNTHVDLRTLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLF
FAILMFAIIGLEFYSGKLHRACFMNNSGILEGFDPPHPCGVQGCPAGYECKDWIGPNDGI
TQFDNILFAVLTVFQ
FRAGMENT NO
FUNCTION Voltage-sensitive calcium channels (VSCC) mediate thes entry of calcium ions into excitable cells and are also involveds in a variety of calcium-dependent processes, including muscles contraction, hormone or neurotransmitter release, gene expression,s ce
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 11031246
1GPR0026Galpha-o-Rattus norvegicus
Family:Gbeta REFERENCES:15251227 | 11031246
2GPR0149Gbeta-1-Rattus norvegicus-2
3GPR0157Gbeta-2-Rattus norvegicus-2
4GPR0162Gbeta-3-Rattus norvegicus
5GPR0166Gbeta-4-Rattus norvegicus
6GPR0169Gbeta-5-Rattus norvegicus
7GPR0396Gbeta-2-Rattus norvegicus-1
8GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:15251227 | 11031246
9GPR0190Ggamma-5-Rattus norvegicus
10GPR0194Ggamma-7-Rattus norvegicus
11GPR0197Ggamma-8-Rattus norvegicus
12GPR0201Ggamma-11-Rattus norvegicus
13GPR0256Ggamma-2-Rattus norvegicus
14GPR0257Ggamma-3-Rattus norvegicus
15GPR0258Ggamma-4-Rattus norvegicus
16GPR0259Ggamma-10-Rattus norvegicus
17GPR0260Ggamma-12-Rattus norvegicus


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