gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0042 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 6

Cross References:
UniProt Q03343 EMBL L01115 | M96160
InterPro IPR001054 | IPR009398
GENEID 25289
PFAM PF06327 | PF00211

Details:
NAME Adenylate cyclase-6-Rattus norvegicus
DESCRIPTION Adenylate cyclase type 6 (EC 4.6.1.1) (Adenylate cyclase type VI) (ATPpyrophosphate-lyase 6) (Adenylyl cyclase 6) (Ca(2+)-inhibitableadenylyl cyclase) (ACVI).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Adcy6
SEQUENCE 
MSWFSGLLVPKVDERKTAWGERNGQKRPRQATRARGFCAPRYMSCLKNVEPPSPTPAART
RCPWQDEAFIRRAGPGRGVKLGLRSVALGFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRL
AQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLTFHAAPALPQPAYVA
LLTCASVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPRSPSAGLWCP
VFFVYITYTLLPIRM
 FRAGMENT NO
FUNCTION Membrane-bound, calcium-inhibitable adenylyl cyclase
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0111Galpha-i3-Rattus norvegicus
2GPR0221Galpha-i1-Rattus norvegicus
3GPR0229Galpha-i2-Rattus norvegicus
4GPR0026Galpha-o-Rattus norvegicus
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
5GPR0124Galpha-s-Rattus norvegicus-2
6GPR0392Galpha-s-Rattus norvegicus-1
Family:Gbeta REFERENCES:15251227 | 15922020 | 14993377 | 11376933
7GPR0149Gbeta-1-Rattus norvegicus-2
8GPR0157Gbeta-2-Rattus norvegicus-2
9GPR0162Gbeta-3-Rattus norvegicus
10GPR0166Gbeta-4-Rattus norvegicus
11GPR0169Gbeta-5-Rattus norvegicus
12GPR0396Gbeta-2-Rattus norvegicus-1
13GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:15251227 | 15922020 | 14993377 | 11376933
14GPR0190Ggamma-5-Rattus norvegicus
15GPR0194Ggamma-7-Rattus norvegicus
16GPR0197Ggamma-8-Rattus norvegicus
17GPR0201Ggamma-11-Rattus norvegicus
18GPR0256Ggamma-2-Rattus norvegicus
19GPR0257Ggamma-3-Rattus norvegicus
20GPR0258Ggamma-4-Rattus norvegicus
21GPR0259Ggamma-10-Rattus norvegicus
22GPR0260Ggamma-12-Rattus norvegicus

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