gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0113 ::
FAMILY Ion channels
SUBFAMILY ATP-sensitive inward rectifier potassium channels
TYPE ATP-sensitive inward rectifier potassium channel 8

Cross References:
UniProt Q63664 | Q9JM49 | Q9JM50 EMBL D42145 | AB043636 | AB043637
InterPro IPR001838 | IPR003278 | IPR013521 | IPR013518
PRODOM PD001103 GENEID 25472
PRINTS PR01331 | PR01320 PFAM PF01007

Details:
NAME ATP-sensitive inward rectifier potassium channel-8-Rattus norvegicus-2
DESCRIPTION ATP-sensitive inward rectifier potassium channel 8 (Potassium channel,inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+)channel Kir6.1) (uKATP-1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Kcnj8
SEQUENCE
MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKGITEKSGLESAVC
VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
VPIHQQDIPVDNPIE
FRAGMENT NO
FUNCTION This potassium channel is controlled by G proteins
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227 | 10990455
1GPR0149Gbeta-1-Rattus norvegicus-2
2GPR0157Gbeta-2-Rattus norvegicus-2
3GPR0162Gbeta-3-Rattus norvegicus
4GPR0166Gbeta-4-Rattus norvegicus
5GPR0169Gbeta-5-Rattus norvegicus
6GPR0396Gbeta-2-Rattus norvegicus-1
7GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:15251227 | 10990455
8GPR0190Ggamma-5-Rattus norvegicus
9GPR0194Ggamma-7-Rattus norvegicus
10GPR0197Ggamma-8-Rattus norvegicus
11GPR0201Ggamma-11-Rattus norvegicus
12GPR0256Ggamma-2-Rattus norvegicus
13GPR0257Ggamma-3-Rattus norvegicus
14GPR0258Ggamma-4-Rattus norvegicus
15GPR0259Ggamma-10-Rattus norvegicus
16GPR0260Ggamma-12-Rattus norvegicus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory