gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0431 ::
FAMILY Ion channels
SUBFAMILY Inwar rectifier K channels
TYPE Kir 3 4(GIRK4)

Cross References:
UniProt P48548 EMBL X83584 | L35771 | D50135 | BC087022
InterPro IPR001838 | IPR003277 | IPR013521 | IPR013518
PRODOM PD001103 GENEID 29713
PRINTS PR01330 | PR01320 PFAM PF01007

Details:
NAME Kir 3.4(GIRK4)-Rattus norvegicus
DESCRIPTION G protein-activated inward rectifier potassium channel 4 (GIRK4)(Potassium channel, inwardly rectifying subfamily J member 5) (Inwardrectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiacinward rectifier) (CIR).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Kcnj5 | Girk4
SEQUENCE 
MAGDSRNAMNQDMEIGVTSQDHKKIPKQARDYIPIATDRTRLLPEGKKPRQRYMEKTGKC
NVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTITWLFFGFIWWLIAYVRGDLDH
VGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNA
FMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIK
SRQTKEGEFIPLNQT
 FRAGMENT NO
FUNCTION This potassium channel is controlled by G proteins
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 14963032 | 11779482
1GPR0111Galpha-i3-Rattus norvegicus
2GPR0221Galpha-i1-Rattus norvegicus
3GPR0229Galpha-i2-Rattus norvegicus
Family:Gq/11 REFERENCES:12661754
4GPR0242Galpha-q-Rattus norvegicus
Family:Gbeta REFERENCES:15251227 | 10944236 | 12661754
5GPR0149Gbeta-1-Rattus norvegicus-2
6GPR0157Gbeta-2-Rattus norvegicus-2
7GPR0162Gbeta-3-Rattus norvegicus
8GPR0166Gbeta-4-Rattus norvegicus
9GPR0169Gbeta-5-Rattus norvegicus
10GPR0396Gbeta-2-Rattus norvegicus-1
11GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:15251227 | 10944236
12GPR0190Ggamma-5-Rattus norvegicus
13GPR0194Ggamma-7-Rattus norvegicus
14GPR0197Ggamma-8-Rattus norvegicus
15GPR0201Ggamma-11-Rattus norvegicus
16GPR0256Ggamma-2-Rattus norvegicus
17GPR0257Ggamma-3-Rattus norvegicus
18GPR0258Ggamma-4-Rattus norvegicus
19GPR0259Ggamma-10-Rattus norvegicus
20GPR0260Ggamma-12-Rattus norvegicus

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