gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0804 ::
FAMILY Small GTP-binding proteins
SUBFAMILY Rho small GTPases
TYPE Rho

Cross References:
UniProt Q6SA80 EMBL AY461427
InterPro IPR003578 | IPR013753 | IPR001806 | IPR005225
GENEID 295588
PRINTS PR00449 PFAM PF00071

Details:
NAME Rho-Rattus norvegicus-9
DESCRIPTION Rho-related GTP-binding protein RhoE precursor (Rho family GTPase 3)(Rnd3).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Rnd3 | Arhe | Rhoe
SEQUENCE
MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
CTVM
FRAGMENT NO
FUNCTION Binds GTP but lacks intrinsic GTPase activity and iss resistant to Rho-specific GTPase-activating proteins (Bys similarity)
Interacting with G-proteins:
Family:Gbeta REFERENCES:15251227
1GPR0149Gbeta-1-Rattus norvegicus-2
2GPR0157Gbeta-2-Rattus norvegicus-2
3GPR0162Gbeta-3-Rattus norvegicus
4GPR0166Gbeta-4-Rattus norvegicus
5GPR0169Gbeta-5-Rattus norvegicus
6GPR0396Gbeta-2-Rattus norvegicus-1
7GPR0397Gbeta-1-Rattus norvegicus-1
Family:Ggamma REFERENCES:15251227
8GPR0190Ggamma-5-Rattus norvegicus
9GPR0194Ggamma-7-Rattus norvegicus
10GPR0197Ggamma-8-Rattus norvegicus
11GPR0201Ggamma-11-Rattus norvegicus
12GPR0256Ggamma-2-Rattus norvegicus
13GPR0257Ggamma-3-Rattus norvegicus
14GPR0258Ggamma-4-Rattus norvegicus
15GPR0259Ggamma-10-Rattus norvegicus
16GPR0260Ggamma-12-Rattus norvegicus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory