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gpDB::G-protein View
Entry 1 of 1 :: GPR0391 ::
CLASS Galpha
FAMILY Gs
SUBFAMILY Galpha-s
TYPE Galpha-s

Cross References:
UniProt Q9JJ33 EMBL AF124384
InterPro IPR001019
PFAM PF00503

Details:
NAME Galpha-s-Mus musculus
DESCRIPTION Guanine nucleotide binding protein, alpha stimulating, extra large.
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
POST TRANSLATION MODIFICATIONS null GENE Gnas | Gnasxl
SEQUENCE 
QVADPPTPRPPPRPTAWPDKYERGRSCCRYEASSGICEIESSSDESEEGATGCFQWLLRR
NRRPGQPRSHTVGSNPVRNFFTRAFGSCFGLSECTRSRSLSPGKAKDPMEERRKQMRKEA
IEMREQKRADKKRSKLIDKQLEEEKMDYMCTHRLLLL
 FRAGMENT YES
FUNCTION -
Effectors:
1EFF0004Adenylate cyclase-1-Mus musculus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
2EFF0005Adenylate cyclase-1-Mus musculus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
3EFF0009Adenylate cyclase-2-Mus musculus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
4EFF0010Adenylate cyclase-2-Mus musculus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
5EFF0014Adenylate cyclase-3-Mus musculus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
6EFF0015Adenylate cyclase-3-Mus musculus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
7EFF0016Adenylate cyclase-3-Mus musculus-3Stimulation15251227 | 15922020 | 14993377 | 11376933
8EFF0017Adenylate cyclase-3-Mus musculus-4Stimulation15251227 | 15922020 | 14993377 | 11376933
9EFF0018Adenylate cyclase-3-Mus musculus-5Stimulation15251227 | 15922020 | 14993377 | 11376933
10EFF0022Adenylate cyclase-4-Mus musculus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
11EFF0023Adenylate cyclase-4-Mus musculus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
12EFF0024Adenylate cyclase-4-Mus musculus-3Stimulation15251227 | 15922020 | 14993377 | 11376933
13EFF0025Adenylate cyclase-4-Mus musculus-4Stimulation15251227 | 15922020 | 14993377 | 11376933
14EFF0032Adenylate cyclase-5-Mus musculus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
15EFF0033Adenylate cyclase-5-Mus musculus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
16EFF0040Adenylate cyclase-6-Mus musculus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
17EFF0041Adenylate cyclase-6-Mus musculus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
18EFF0046Adenylate cyclase-7-Mus musculus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
19EFF0047Adenylate cyclase-7-Mus musculus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
20EFF0048Adenylate cyclase-7-Mus musculus-3Stimulation15251227 | 15922020 | 14993377 | 11376933
21EFF0049Adenylate cyclase-7-Mus musculus-4Stimulation15251227 | 15922020 | 14993377 | 11376933
22EFF0050Adenylate cyclase-7-Mus musculus-5Stimulation15251227 | 15922020 | 14993377 | 11376933
23EFF0051Adenylate cyclase-7-Mus musculus-6Stimulation15251227 | 15922020 | 14993377 | 11376933
24EFF0057Adenylate cyclase-8-Mus musculus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
25EFF0058Adenylate cyclase-8-Mus musculus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
26EFF0063Adenylate cyclase-9-Mus musculus-1Stimulation15251227 | 15922020 | 14993377 | 11376933
27EFF0064Adenylate cyclase-9-Mus musculus-2Stimulation15251227 | 15922020 | 14993377 | 11376933
28EFF0859Src tyrosine kinase-Mus musculus-1Stimulation11007482 | 15251227 | 12209124
29EFF0860Src tyrosine kinase-Mus musculus-2Stimulation11007482 | 15251227 | 12209124
30EFF0861Src tyrosine kinase-Mus musculus-3Stimulation11007482 | 15251227 | 12209124
31EFF0862Src tyrosine kinase-Mus musculus-4Stimulation11007482 | 15251227 | 12209124
32EFF0863Src tyrosine kinase-Mus musculus-5Stimulation11007482 | 15251227 | 12209124
33EFF0864Src tyrosine kinase-Mus musculus-6Stimulation11007482 | 15251227 | 12209124
34EFF0865Src tyrosine kinase-Mus musculus-7Stimulation11007482 | 15251227 | 12209124
35EFF0866Src tyrosine kinase-Mus musculus-8Stimulation11007482 | 15251227 | 12209124
36EFF1192Tubulin-Mus musculus-1Stimulation of GTPase activity10224115 | 15251227 | 16380086
37EFF1193Tubulin-Mus musculus-10Stimulation of GTPase activity10224115 | 15251227 | 16380086
38EFF1194Tubulin-Mus musculus-11Stimulation of GTPase activity10224115 | 15251227 | 16380086
39EFF1195Tubulin-Mus musculus-12Stimulation of GTPase activity10224115 | 15251227 | 16380086
40EFF1202Tubulin-Mus musculus-19Stimulation of GTPase activity10224115 | 15251227 | 16380086
41EFF1203Tubulin-Mus musculus-2Stimulation of GTPase activity10224115 | 15251227 | 16380086
42EFF1209Tubulin-Mus musculus-25Stimulation of GTPase activity10224115 | 15251227 | 16380086
43EFF1214Tubulin-Mus musculus-3Stimulation of GTPase activity10224115 | 15251227 | 16380086
44EFF1217Tubulin-Mus musculus-32Stimulation of GTPase activity10224115 | 15251227 | 16380086
45EFF1218Tubulin-Mus musculus-33Stimulation of GTPase activity10224115 | 15251227 | 16380086
46EFF1220Tubulin-Mus musculus-35Stimulation of GTPase activity10224115 | 15251227 | 16380086
47EFF1221Tubulin-Mus musculus-34Stimulation of GTPase activity10224115 | 15251227 | 16380086
48EFF1223Tubulin-Mus musculus-31Stimulation of GTPase activity10224115 | 15251227 | 16380086
49EFF1225Tubulin-Mus musculus-4Stimulation of GTPase activity10224115 | 15251227 | 16380086
50EFF1226Tubulin-Mus musculus-30Stimulation of GTPase activity10224115 | 15251227 | 16380086
51EFF1227Tubulin-Mus musculus-29Stimulation of GTPase activity10224115 | 15251227 | 16380086
52EFF1228Tubulin-Mus musculus-28Stimulation of GTPase activity10224115 | 15251227 | 16380086
53EFF1230Tubulin-Mus musculus-27Stimulation of GTPase activity10224115 | 15251227 | 16380086
54EFF1231Tubulin-Mus musculus-26Stimulation of GTPase activity10224115 | 15251227 | 16380086
55EFF1232Tubulin-Mus musculus-24Stimulation of GTPase activity10224115 | 15251227 | 16380086
56EFF1233Tubulin-Mus musculus-23Stimulation of GTPase activity10224115 | 15251227 | 16380086
57EFF1235Tubulin-Mus musculus-22Stimulation of GTPase activity10224115 | 15251227 | 16380086
58EFF1236Tubulin-Mus musculus-5Stimulation of GTPase activity10224115 | 15251227 | 16380086
59EFF1237Tubulin-Mus musculus-21Stimulation of GTPase activity10224115 | 15251227 | 16380086
60EFF1238Tubulin-Mus musculus-20Stimulation of GTPase activity10224115 | 15251227 | 16380086
61EFF1239Tubulin-Mus musculus-18Stimulation of GTPase activity10224115 | 15251227 | 16380086
62EFF1240Tubulin-Mus musculus-17Stimulation of GTPase activity10224115 | 15251227 | 16380086
63EFF1241Tubulin-Mus musculus-16Stimulation of GTPase activity10224115 | 15251227 | 16380086
64EFF1242Tubulin-Mus musculus-15Stimulation of GTPase activity10224115 | 15251227 | 16380086
65EFF1243Tubulin-Mus musculus-14Stimulation of GTPase activity10224115 | 15251227 | 16380086
66EFF1244Tubulin-Mus musculus-13Stimulation of GTPase activity10224115 | 15251227 | 16380086
67EFF1245Tubulin-Mus musculus-6Stimulation of GTPase activity10224115 | 15251227 | 16380086
68EFF1246Tubulin-Mus musculus-7Stimulation of GTPase activity10224115 | 15251227 | 16380086
69EFF1247Tubulin-Mus musculus-8Stimulation of GTPase activity10224115 | 15251227 | 16380086
70EFF1248Tubulin-Mus musculus-9Stimulation of GTPase activity10224115 | 15251227 | 16380086

Coupling with GPCRs:
1GPCR00915-HYDROXYTRYPTAMINE RECEPTOR_5-HT-4_Mus musculus2849052
2GPCR01005-HYDROXYTRYPTAMINE RECEPTOR_5-HT-6_Mus musculus8522988
3GPCR01055-HYDROXYTRYPTAMINE RECEPTOR_5-HT-7_Mus musculus8397408
4GPCR0184ADENOSINE RECEPTOR_A2A_Mus musculus1662665
5GPCR0233ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2A(Adrenoceptor)_Mus musculus8662784
6GPCR0186ADENOSINE RECEPTOR_A2B_Mus musculus11048721
7GPCR2571CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_ADRENOMEDULIN RECEPTOR_Mus musculus8549809
8GPCR0306ADRENOCEPTOR (B-ADRENOCEPTOR)_B1(Adrenoceptor)_Mus musculus-12825170
9GPCR0314ADRENOCEPTOR (B-ADRENOCEPTOR)_B1(Adrenoceptor)_Mus musculus-22825170
10GPCR0322ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Mus musculus-23041227
11GPCR0357ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Mus musculus-13041227
12GPCR0400ADRENOCEPTOR (B-ADRENOCEPTOR)_B3(Adrenoceptor)_Mus musculus2570461
13GPCR2575CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CALCITONIN_Mus musculus1331173
14GPCR0733CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK1_Mus musculus8503909
15GPCR2581CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CGRP_Mus musculus2542467
16GPCR2585CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF1_Mus musculus1280419
17GPCR2589CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF2_Mus musculus8536644
18GPCR0752DOPAMINE RECEPTOR_D1_Mus musculus-22144334
19GPCR0761DOPAMINE RECEPTOR_D1_Mus musculus-12144334
20GPCR2416PROSTANOID RECEPTOR_DP_Mus musculus7512962
21GPCR2424PROSTANOID RECEPTOR_EP2_Mus musculus7910583
22GPCR2430PROSTANOID RECEPTOR_EP3_Mus musculus11095474
23GPCR2437PROSTANOID RECEPTOR_EP4_Mus musculus8016385
24GPCR0815ENDOTHELIN RECEPTOR_ET-A_Mus musculus1849646
25GPCR0852GLYCOPROTEIN HORMONE RECEPTOR_FSH RECEPTOR_Mus musculus9139796
26GPCR2600GLUCAGON RECEPTOR_GLUCAGON-LIKE PEPTIDE RECEPTOR_Mus musculus1326760
27GPCR2596GLUCAGON RECEPTOR_GLUCAGON RECEPTOR_Mus musculus8144028
28GPCR0971HISTAMINE RECEPTOR_H2_Mus musculus-11703298
29GPCR0973HISTAMINE RECEPTOR_H2_Mus musculus-21703298
30GPCR0975HISTAMINE RECEPTOR_H2_Mus musculus-41703298
31GPCR0979HISTAMINE RECEPTOR_H2_Mus musculus-31703298
32GPCR2444PROSTANOID RECEPTOR_IP_Mus musculus7512962
33GPCR0877GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Mus musculus1516719
34GPCR1168MELANOCORTIN RECEPTOR_MC1_Mus musculus1516719
35GPCR1180MELANOCORTIN RECEPTOR_MC2_Mus musculus1325670
36GPCR1190MELANOCORTIN RECEPTOR_MC3_Mus musculus8463333
37GPCR1193MELANOCORTIN RECEPTOR_MC4_Mus musculus8392067
38GPCR1208MELANOCORTIN RECEPTOR_MC5_Mus musculus8185570
39GPCR2500TACHYKININ RECEPTOR_NK1_Mus musculus1370820
40GPCR2508TACHYKININ RECEPTOR_NK2_Mus musculus1370820
41GPCR2512TACHYKININ RECEPTOR_NK3_Mus musculus1370820
42GPCR2619VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_PAC1_Mus musculus8396727
43GPCR2612PARATHYROID HORMONE RECEPTOR_PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR_Mus musculus1658941
44GPCR1105LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Mus musculus-312220620
45GPCR1114LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Mus musculus-112220620
46GPCR1123LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Mus musculus-212220620
47GPCR1128LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Mus musculus-412220620
48GPCR1129TRACE AMINE RECEPTOR_TaR_Mus musculus11459929
49GPCR2531TRACE AMINE RECEPTOR_TaR-1_Mus musculus11459929
50GPCR0897GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Mus musculus-18552586
51GPCR2624VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC1_Mus musculus-11675791
52GPCR2628VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC1_Mus musculus-21675791
53GPCR2635VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC2_Mus musculus7733904



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