gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2575 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR
SUBFAMILY CALCITONIN

Cross References:
UniProt Q60755 EMBL U18542
InterPro IPR003287 | IPR001688 | IPR001879 | IPR000832 GPCRDB calcr_mouse
PRINTS PR00361 | PR01350 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CALCITONIN_Mus musculus
DESCRIPTION Calcitonin receptor precursor (CT-R).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Calcr
SEQUENCE
MRFLLVNRFTLLLLLLVSPTPVLQAPTNLTDSGLDQEPFLYLVGRKKLLDAQYKCYDRIH
QLPSYEGEGLYCNRTWDGWMCWDDTPAGATAYQHCPDYFPDFDTAEKVSKYCDENGEWFR
HPDSNRTWSNYTLCNAFTSEKLQNAYVLYYLALVGHSLSIAALVASMLIFWIFKNLSCQR
VTLHKHMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTHMWTMQWELSPPLPLC
AHEGKMDPHASEVISCKVLHFLHQYMMSCNYFWMLCEGIYLHTLIVMAVFTDEQRLRWYY
LLGWGFPIVPTIIHAITRALYYNDNCWLSAETHLLYIIHGPVMVALVVNFFFLLNIVRVL
VTKMRQTHEAESYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQ
GFFVATIYCFCNHEVQVTLKRQWTQFKIQWSQRWGRRRPTNRVVSAPRAVAFAEPDGLPI
YICHQEPRNPPISNNEGEESTEMIPMNVIQQDASA
FRAGMENT NO

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Scaffold:
TYPE alpha-filamin/ABP280( actin binding protein 280) REFERENCES 12531889

Coupling with G-proteins:
Family:Gq/11 REFERENCES:8732687
1GPR0031Galpha-11-Mus musculus-2
2GPR0240Galpha-q-Mus musculus
3GPR0360Galpha-11-Mus musculus-1
Family:Gs REFERENCES:1331173
4GPR0123Galpha-s-Mus musculus-2
5GPR0391Galpha-s-Mus musculus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory