gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2430 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROSTANOID RECEPTOR
SUBFAMILY EP3

Cross References:
UniProt P30557 EMBL D10204 | D13321 | D17406
InterPro IPR000154 | IPR000276 | IPR008365 | IPR001244 | IPR000265 GPCRDB pe2r3_mouse
PRINTS PR00237 | PR00428 | PR01788 | PR00585 | PR00582 PFAM PF00001

Details:
NAME PROSTANOID RECEPTOR_EP3_Mus musculus
DESCRIPTION Prostaglandin E2 receptor EP3 subtype (Prostanoid EP3 receptor) (PGEreceptor, EP3 subtype).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Ptger3 | Ptgerep3
SEQUENCE
MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESK
RKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLS
SLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWP
GTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKA
AVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKE
CNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWS
DQLER
FRAGMENT NO

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Scaffold:
TYPE Muskelin REFERENCES 11006128

Coupling with G-proteins:
Family:Gi/o REFERENCES:11095474
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:11095474
6GPR0031Galpha-11-Mus musculus-2
7GPR0240Galpha-q-Mus musculus
8GPR0360Galpha-11-Mus musculus-1
Family:Gs REFERENCES:11095474
9GPR0123Galpha-s-Mus musculus-2
10GPR0391Galpha-s-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory