gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0971 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY HISTAMINE RECEPTOR
SUBFAMILY H2

Cross References:
UniProt P97292 EMBL D50096
InterPro IPR000276 | IPR000503 GPCRDB hrh2_mouse
PRINTS PR00237 | PR00531 PFAM PF00001

Details:
NAME HISTAMINE RECEPTOR_H2_Mus musculus-1
DESCRIPTION Histamine H2 receptor (H2R) (Gastric receptor I).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Hrh2
SEQUENCE
MEPNGTVHSCCLDSIALKVTISVVLTTLIFITVAGNVVVCLAVSLNRRLRSLTNCFIVSL
AATDLLLGLLVMPFSAIYQLSFKWRFGQVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEV
YGLVDGMVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMG
AFIVCWFPYFTAFVYRGLRGDDPVNEVVEGIVLWLGYANSALNPILYATLNRDFRMAYQQ
LFHCKLASHNSHKTSLRLNNSLLSRSQSREGRWQEEKPLKLQVWSGTELTHPQGSPVR
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 9202162

Coupling with G-proteins:
Family:Gs REFERENCES:1703298
1GPR0123Galpha-s-Mus musculus-2
2GPR0391Galpha-s-Mus musculus


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athina University of Athens
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Biophysics
& Bioinformatics
Laboratory