gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0032 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 5

Cross References:
UniProt P84309 | Q3TU67 | Q3UH09 | Q5BL06 EMBL AK147649 | AK160942 | BC035550 | BC090846
InterPro IPR001054 | IPR009398
GENEID 224129
PFAM PF06327 | PF00211

Details:
NAME Adenylate cyclase-5-Mus musculus-1
DESCRIPTION Adenylate cyclase type 5 (EC 4.6.1.1) (Adenylate cyclase type V) (ATPpyrophosphate-lyase 5) (Adenylyl cyclase 5).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Adcy5
SEQUENCE
MSGSKSVSPPGYAAQTAASPAPRGGPEHRAAWGEADSRANGYPHAPGGSTRGSTKRSGGA
VTPQQQQRLASRWRGGDDDEDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDGGRGSRRQR
RGAAGGGSTRAPPAGGSGSSAAAAAAAGGTEVRPRSVELGLEERRGKGRAAEELEPGTGI
VEDGDGSEDGGSSVASGSGTGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQ
SSLTMLMAVLVLVCL
FRAGMENT NO
FUNCTION This is a membrane-bound, calcium-inhibitable adenylyls cyclase
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0227Galpha-i2-Mus musculus-2
2GPR0289Galpha-i1-Mus musculus
3GPR0331Galpha-i2-Mus musculus-1
4GPR0385Galpha-i3-Mus musculus
5GPR0021Galpha-o1-Mus musculus
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
6GPR0123Galpha-s-Mus musculus-2
7GPR0391Galpha-s-Mus musculus
Family:Gbeta REFERENCES:15251227 | 15922020 | 14993377 | 11376933
8GPR0148Gbeta-1-Mus musculus
9GPR0156Gbeta-2-Mus musculus
10GPR0161Gbeta-3-Mus musculus
11GPR0165Gbeta-4-Mus musculus
12GPR0168Gbeta-5-Mus musculus-2
13GPR0291unclassified_Gbeta-Mus musculus-1
14GPR0318unclassified_Gbeta-Mus musculus-2
15GPR0376Gbeta-5-Mus musculus-3
16GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 15922020 | 14993377 | 11376933
17GPR0178Ggamma-t1-Mus musculus
18GPR0181Ggamma-2-Mus musculus
19GPR0184Ggamma-3-Mus musculus
20GPR0186Ggamma-4-Mus musculus
21GPR0189Ggamma-5-Mus musculus
22GPR0193Ggamma-7-Mus musculus
23GPR0196Ggamma-8-Mus musculus-2
24GPR0200Ggamma-11-Mus musculus
25GPR0204Ggamma-12-Mus musculus
26GPR0206Ggamma-13-Mus musculus
27GPR0211Ggamma-8-Mus musculus-1
28GPR0349Ggamma-1-Mus musculus
29GPR0379Ggamma-10-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory