gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0186 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADENOSINE RECEPTOR
SUBFAMILY A2B

Cross References:
UniProt Q60614 EMBL U05673
InterPro IPR001435 | IPR001634 | IPR000276 GPCRDB aa2br_mouse
PRINTS PR00554 | PR00424 | PR00237 PFAM PF00001

Details:
NAME ADENOSINE RECEPTOR_A2B_Mus musculus
DESCRIPTION Adenosine receptor A2b.
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Adora2b
SEQUENCE
MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFA
IPFAITISLGFCTDFHGCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGT
RARGIIAVLWVLAFGIGLTPFLGWNSKDSATSNCTELGDGIANKSCCPLTCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFMVACKQLQSMELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYS
FHKIISRYVLCQAETKGGSGQAGAQSTLSLGL
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12804599

Coupling with G-proteins:
Family:Gs REFERENCES:11048721
1GPR0123Galpha-s-Mus musculus-2
2GPR0391Galpha-s-Mus musculus


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athina University of Athens
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Biophysics
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Laboratory