gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0043 ::
CLASS Galpha
FAMILY Gq/11
SUBFAMILY Galpha-15/16
TYPE Galpha-16

Cross References:
UniProt P30679 | O75247 EMBL M63904 | AF493904 | AC005264 | AC005262 | BC013585
InterPro IPR001019 | IPR000654 | IPR011025
PRODOM PD000281
MIM 139314
PRINTS PR00318 | PR00442 PFAM PF00503

Details:
NAME Galpha-16-Homo sapiens
DESCRIPTION Guanine nucleotide-binding protein alpha-15 subunit (G alpha-15) (Galpha-16).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
POST TRANSLATION MODIFICATIONS null GENE GNA15 | GNA16
SEQUENCE 
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD
PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ
DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ
CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG
PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR
DSVLARYLDEINLL
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0375GRK6-Homo sapiens-1Stimulation14654303
2EFF0376GRK6-Homo sapiens-2Stimulation14654303
3EFF0517Phospholipase C beta-1-Homo sapiens-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
4EFF0521Phospholipase C beta-1-Homo sapiens-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
5EFF0522Phospholipase C beta-1-Homo sapiens-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
6EFF0530Phospholipase C beta-2-Homo sapiens-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
7EFF0531Phospholipase C beta-2-Homo sapiens-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
8EFF0541Phospholipase C beta-3-Homo sapiens-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
9EFF0542Phospholipase C beta-3-Homo sapiens-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
10EFF0556Phospholipase C beta-4-Homo sapiens-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
11EFF0558Phospholipase C beta-4-Homo sapiens-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
12EFF0560Phospholipase C beta-4-Homo sapiens-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
13EFF0877TRP repeat protein-1-Homo sapiensG16a co-expression enhances TPR1 interaction with Ras16182515 | 12748287

Coupling with GPCRs:
1GPCR0709CHEMOTACTIC PEPTIDE RECEPTOR_C5A_Homo sapiens-27870028
2GPCR0711CHEMOTACTIC PEPTIDE RECEPTOR_C5A_Homo sapiens-17870028



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