gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0376 ::
FAMILY Ser Thr protein kinases
SUBFAMILY G protein coupled receptor kinases
TYPE GRK6

Cross References:
UniProt P43250 | O60541 | Q13652 EMBL L16862 | AF040751 | AF040752 | BC009277 | U00686
InterPro IPR000239 | IPR000961 | IPR000719 | IPR000342 | IPR008271 | IPR002290 PDB 2ACX
PRODOM PD000001 GENEID 2870 MIM 600869
PRINTS PR00717 PFAM PF00069 | PF00615

Details:
NAME GRK6-Homo sapiens-2
DESCRIPTION G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupledreceptor kinase GRK6).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE GRK6 | GPRK6
SEQUENCE 
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE
VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
VNSRFVVSLAYAYET
 FRAGMENT NO
FUNCTION Specifically phosphorylates the activated forms of Gs protein-coupled receptors
Interacting with G-proteins:
Family:Gq/11 REFERENCES:14654303
1GPR0043Galpha-16-Homo sapiens

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
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& Bioinformatics
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