gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0033 ::
CLASS Galpha
FAMILY Gq/11
SUBFAMILY Galpha-11
TYPE Galpha-11

Cross References:
UniProt P43444 EMBL U10494
InterPro IPR001019 | IPR000654 | IPR011025
PRODOM PD000281
GENEID 779103
PRINTS PR00318 | PR00442 PFAM PF00503

Details:
NAME Galpha-11-Xenopus laevis-2
DESCRIPTION Guanine nucleotide-binding protein alpha-11 subunit.
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
POST TRANSLATION MODIFICATIONS null GENE gna11
SEQUENCE
MTLDSTMACCLSEEVKESKRINAEIEKQLRRDKKDSRRELKLLLLGTGESGKSTFIKQMR
IIHGSGYSEEDKKGFTKLVFQNIFTAMQSMIRAMETLKILYKYEQNKANAQVVREVDVEK
VCTFEQPYVNAIKNLWSDPGIQECYDRRREYQLSDSTKYYLTDVDRISKPGYLPTQQDVL
RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV
ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKIMYSHLVDYFPEFDGPQR
DAATAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0368GRK4-Xenopus laevis-1Stimulation15251227 | 14654303
2EFF0369GRK4-Xenopus laevis-2Stimulation15251227 | 14654303

Coupling with GPCRs:
1GPCR0410ANGIOTENSIN RECEPTOR_AT1_Xenopus laevis-18865167
2GPCR0415ANGIOTENSIN RECEPTOR_AT1_Xenopus laevis-28865167
3GPCR0736CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK1_Xenopus laevis8503909
4GPCR2729FRIZZLED_Frizzled-1_Xenopus laevis11563835
5GPCR2741FRIZZLED_Frizzled-2_Xenopus laevis11563835
6GPCR1017LYSOPHOSPHOLIPID RECEPTOR_LPA3_Xenopus laevis12215548
7GPCR0876GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Xenopus laevis1516719
8GPCR2457PROTEASE-ACTIVATED RECEPTOR_PAR1_Xenopus laevis10644723
9GPCR1252NEUROPEPTIDE Y RECEPTOR_Y1_Xenopus laevis1321422




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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory