gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2741 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY FRIZZLED
SUBFAMILY Frizzled-2

Cross References:
UniProt Q9PUU6 | Q2TAR6 EMBL AF139165 | BC110756
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB fzd2_xenla
GENEID 399141
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME FRIZZLED_Frizzled-2_Xenopus laevis
DESCRIPTION Frizzled-2 precursor (Fz-2) (Xfz2).
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
GENE fzd2 | fz2
SEQUENCE
MQGVTRASILLIIYHLFTLSLGQLHGEKGISVPEHGFCQPISIPLCTDIAYNQTIMPNLL
GHTNQEDAGLEVHQFYPLVKVQCSSELRFFLCSMYAPVCTVLEQAIPPCRSICERARHGC
EALMNKFGFQWPERLRCENFPRHGAEQICVGQNHSEDGGPTLLTTSPPHHGTPGPPIYAT
LDHPFHCPRVLKVPSYLNYRFLGEKDCAAPCEPTKSDGFMFFSQDEIRFARIWILIWSVL
CCASTFITVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLGDKVVCNEGFSEDG
YKTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHL
AAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNNIDPLRGFVLAPLFVYLFIGTSFLLAG
FVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSW
VSQNCKSLAIPCPLQYTPRMTPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTR
LTNSKHGETTV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:11563835
1GPR0033Galpha-11-Xenopus laevis-2
2GPR0243Galpha-q-Xenopus laevis
3GPR0314Galpha-11-Xenopus laevis-1
Family:Gi/o REFERENCES:11563835
4GPR0244Galpha-t-Xenopus laevis


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory