gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2729 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY FRIZZLED
SUBFAMILY Frizzled-1

Cross References:
UniProt Q9I9M5 EMBL AF231711
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB fzd1_xenla
GENEID 373817
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME FRIZZLED_Frizzled-1_Xenopus laevis
DESCRIPTION Frizzled-1 precursor (Fz-1) (Xfz1).
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
GENE fzd1 | fz1
SEQUENCE 
MKHSHLLQRCSAQLCTRGSSLILSLLLSVCLSVEGQYNGEKGISIPDHGYCQPISIPLCT
DIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELKFFLCSIYAPVCTVLEQALP
PCRSLCDRARQGCEALMNKFGFQWPESLRCEKFPINGAGELCVGQNTTESGTPTPAVPET
WTSNSRTYYRDKFMCPRALKVPAYVNYHFLGEKDCGAPCEVGKVHGLMYFAPEELNFARI
WIGIWSVLCCASTLFTVLTYLVDMKRFSYPERPIIFLSGCYTMVAIAYIAGFLLEDKVVC
NERFAEDGYKTVAQGTKKEGCTFLFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIE
ANSQYFHLAAWAVPAIKTITILAVGQVDGDTLSGVCFVGINNVDALRGFVLAPLFVYLFI
GTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGIFSVLYTVPATIVIACYFYEQAF
REQWEKSWISQSCKTYAIPCPSTGHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLN
SWRKFYTRLTNSKQGETTV
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11563835
1GPR0016Galpha-o-Xenopus laevis
2GPR0112Galpha-i3-Xenopus laevis
3GPR0222Galpha-i1-Xenopus laevis
4GPR0271Galpha-o1-Xenopus laevis
5GPR0272Galpha-i-Xenopus laevis
Family:Gq/11 REFERENCES:11563835
6GPR0033Galpha-11-Xenopus laevis-2
7GPR0243Galpha-q-Xenopus laevis
8GPR0314Galpha-11-Xenopus laevis-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory