gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0298 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-i
TYPE Galpha-i2

Cross References:
UniProt Q7ZWI5 EMBL BC049343
InterPro IPR001019 | IPR001408 | IPR011025
PRODOM PD000281
GENEID 327650
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-i2-Danio rerio-1
DESCRIPTION Guanine nucleotide binding protein (G protein), alpha inhibitingactivity polypeptide 2.
SPECIES Danio rerio COMMON NAME Zebrafish NCBI Taxonomy 7955
POST TRANSLATION MODIFICATIONS null GENE gnai2
SEQUENCE 
MGCTVSAEDKAAAERSKMIDKNLREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQ
YRAVVYSNTIQSIMAIIKAMSNLKIDYGESARVDDARQLFALSAAAEEQGILTDDLANVI
RRLWADSGVQGCFSRSREYQLNDSAAYYLNDLDRIARSDYIPTQQDVLRTRVKTTGIVET
HFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESM
KLFDSICNNKWFTETSIILFLNKKDLFEEKITRSPLTICFPEYSGANKYDEAASYIQTKF
EDLNKKKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
 FRAGMENT NO
FUNCTION -
Effectors:
1EFF0612Rac-Danio rerio -1Stimulation11099498
2EFF0613Rac-Danio rerio -2Stimulation11099498
3EFF0614Rac-Danio rerio -3Stimulation11099498
4EFF0615Rac-Danio rerio -4Stimulation11099498
5EFF0616Rac-Danio rerio -5Stimulation11099498
6EFF0846Src tyrosine kinase-Danio rerioStimulation11007482 | 15251227 | 12209124
7EFF0954Tubulin-Danio rerio -1Stimulation of GTPase activity10224115 | 15251227 | 16380086
8EFF0955Tubulin-Danio rerio -10Stimulation of GTPase activity10224115 | 15251227 | 16380086
9EFF0956Tubulin-Danio rerio -11Stimulation of GTPase activity10224115 | 15251227 | 16380086
10EFF0957Tubulin-Danio rerio -12Stimulation of GTPase activity10224115 | 15251227 | 16380086
11EFF0958Tubulin-Danio rerio -13Stimulation of GTPase activity10224115 | 15251227 | 16380086
12EFF0959Tubulin-Danio rerio -14Stimulation of GTPase activity10224115 | 15251227 | 16380086
13EFF0960Tubulin-Danio rerio -15Stimulation of GTPase activity10224115 | 15251227 | 16380086
14EFF0961Tubulin-Danio rerio -16Stimulation of GTPase activity10224115 | 15251227 | 16380086
15EFF0962Tubulin-Danio rerio -17Stimulation of GTPase activity10224115 | 15251227 | 16380086
16EFF0963Tubulin-Danio rerio -18Stimulation of GTPase activity10224115 | 15251227 | 16380086
17EFF0964Tubulin-Danio rerio -19Stimulation of GTPase activity10224115 | 15251227 | 16380086
18EFF0965Tubulin-Danio rerio -2Stimulation of GTPase activity10224115 | 15251227 | 16380086
19EFF0966Tubulin-Danio rerio -20Stimulation of GTPase activity10224115 | 15251227 | 16380086
20EFF0967Tubulin-Danio rerio -21Stimulation of GTPase activity10224115 | 15251227 | 16380086
21EFF0968Tubulin-Danio rerio -22Stimulation of GTPase activity10224115 | 15251227 | 16380086
22EFF0969Tubulin-Danio rerio -23Stimulation of GTPase activity10224115 | 15251227 | 16380086
23EFF0970Tubulin-Danio rerio -24Stimulation of GTPase activity10224115 | 15251227 | 16380086
24EFF0971Tubulin-Danio rerio -25Stimulation of GTPase activity10224115 | 15251227 | 16380086
25EFF0972Tubulin-Danio rerio -26Stimulation of GTPase activity10224115 | 15251227 | 16380086
26EFF0973Tubulin-Danio rerio -27Stimulation of GTPase activity10224115 | 15251227 | 16380086
27EFF0974Tubulin-Danio rerio -28Stimulation of GTPase activity10224115 | 15251227 | 16380086
28EFF0975Tubulin-Danio rerio -3Stimulation of GTPase activity10224115 | 15251227 | 16380086
29EFF0976Tubulin-Danio rerio -4Stimulation of GTPase activity10224115 | 15251227 | 16380086
30EFF0977Tubulin-Danio rerio -5Stimulation of GTPase activity10224115 | 15251227 | 16380086
31EFF0978Tubulin-Danio rerio -6Stimulation of GTPase activity10224115 | 15251227 | 16380086
32EFF0979Tubulin-Danio rerio -7Stimulation of GTPase activity10224115 | 15251227 | 16380086
33EFF0980Tubulin-Danio rerio -8Stimulation of GTPase activity10224115 | 15251227 | 16380086
34EFF0981Tubulin-Danio rerio -9Stimulation of GTPase activity10224115 | 15251227 | 16380086

Coupling with GPCRs:
1GPCR0238ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2A(Adrenoceptor)_Brachydanio rerio8662784
2GPCR0288ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2B(Adrenoceptor)_Brachydanio rerio2164221
3GPCR0300ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2C(Adrenoceptor)_Brachydanio rerio2842764
4GPCR0645CHEMOKINE RECEPTOR (CX3C)_CXCR4_Brachydanio rerio -28629022
5GPCR0650CHEMOKINE RECEPTOR (CX3C)_CXCR4_Brachydanio rerio -18629022
6GPCR1215MELATONIN RECEPTOR_MT1_Brachydanio rerio -17946354
7GPCR1226MELATONIN RECEPTOR_MT1_Brachydanio rerio -27946354
8GPCR1229MELATONIN RECEPTOR_MT2_Brachydanio rerio -112721330
9GPCR1230MELATONIN RECEPTOR_MT2_Brachydanio rerio -212721330
10GPCR1908OPIOID AND OPIOID-LIKE RECEPTOR_MU OPIOID PEPTIDE (MOR)_Brachydanio rerio8393525
11GPCR1068LYSOPHOSPHOLIPID RECEPTOR_S1P1_Brachydanio rerio9488656
12GPCR1091LYSOPHOSPHOLIPID RECEPTOR_S1P2_Brachydanio rerio10488065
13GPCR2805SMOOTHENED_smoothened_Brachydanio rerio -210835429
14GPCR2806SMOOTHENED_smoothened_Brachydanio rerio -310835429
15GPCR2808SMOOTHENED_smoothened_Brachydanio rerio -110835429



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