gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2808 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY SMOOTHENED
SUBFAMILY smoothened

Cross References:
UniProt Q5RH73 EMBL BX571796
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000583 | IPR000832 GPCRDB q5rh73_danre
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME SMOOTHENED_smoothened_Brachydanio rerio -1
DESCRIPTION Smoothened homolog (Drosophila).
SPECIES Danio rerio COMMON NAME Zebrafish NCBI Taxonomy 7955
GENE smo | smoh | DKEY-180P18.4-001
SEQUENCE
MSSKRPCSIVGSFWMLWIWTATSMVARAVILHPNETIFNDFCKKSTTCEVLKYNTCLGSP
LPYTHTSLILAEDSETQEEAFEKLAMWSGLRNAPRCWAVIQPLLCAVYMPKCENGKVELP
SQHLCQATRNPCSIVERERGWPNFLKCENKEQFPKGCQNEVQKLKFNTSGQCEAPLVKTD
IQASWYKDVEGCGIQCDNPLFTEDEHSDMHSYIAVFGTITLLCTFFTLATFLADWKNSNR
YPAVILFYVNACFFIGSIGWLAQFMDGARNEIVCKSDNTMRLGEPSSTETLSCVIIFVIV
YYSLMSGVIWFVMLTYAWHTSFKALGTTHQPLSGKTSYFHLVTWSIPFILTVAILANSQV
DADSVSGICFVGYRYYEYRAGFVLAPIGFVLVIGGYFLIRGVMTLFSIKSNHPGLLSEKA
ASKINETMLRLGIFGFLAFGFVLITFGCHFYDFFNQAEWERSFREYVLCEANVTIAHQTN
KPIPECAIKNRPSLLVGKINLFSMFGTGIAMSTWVWTKATILIWKRTWFRIIGRSDDEPK
RIKKSKMIAKAFSKRKELQKDPEKELSFSMHTVSHEGPVAGINFDLNEPSIEMSSAWAQH
VTKMVARRGAILPQDISVTPTGTPIPPPEERNKLWMVEAEISPEMMKRKKKKKKRRKEVR
PAGPAADEGNPAYHRREFGPSAVPRLPKLPGHRSLVANLWEQQRQQQEEQDMLPGAFPEF
RPSCPLPYQDRYGGLGYLRNKPSSLPLANPLTLRDSMQGDLSHFQQSSWQPKGVFRHLGQ
EASMMDVGRTAVVPRADGRRGVQIHSRTNLMDAELLDADSDF
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:10835429
1GPR0005Galpha-i2-Danio rerio-2
2GPR0298Galpha-i2-Danio rerio-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory