gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2805 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY SMOOTHENED
SUBFAMILY smoothened

Cross References:
UniProt Q90YY4 EMBL AF395809
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB q90yy4_danre
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME SMOOTHENED_smoothened_Brachydanio rerio -2
DESCRIPTION Smoothened.
SPECIES Danio rerio COMMON NAME Zebrafish NCBI Taxonomy 7955
GENE smo | smoh
SEQUENCE
MLWIWTATSMVARAVILHPNETIFNDFCKKSTTCEVLKYNTCLGSPLPYTHTSLILAEDS
ETQEEAFEKLAMWSGLRNAPRCWAVIQPLLCAVYMPKCENGKVELPSQHLCQATRNPCSI
VERERGWPNFLKCENKEQFPKGCQNEVQKLKFNTSGQCEAPLVKTDIQASWYKDVEGCGI
QCDNPLFTEDEHSDMHSYIAVFGTITLLCTFFTLATFLADWKNSNRYPAVILFYVNACFF
IGSIGWLAQFMDGARNEIVCKSDNTMRLGEPSSTETLSCVIIFVIVYYSLMSGVIWFVML
TYAWHTSFKALGTTHQPLSGKTSYFHLVTWSIPFILTVAILANSQVDADSVSGICFVGYR
YYEYRAGFVLAPIGFVLVIGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIF
GFLAFGFVLITFGCHFYDFFNQAEWERSFREYVLCEANVTIAHQTNKPIPECAIKNRPSL
LVGKINLFSMFGTGIAMSTWVWTKATILIWKRTWFRIIGRSDDEPKRIKKSKMIAKAFSK
RKELQKDPEKELSFSMHTVSHEGPVAGINFDLNEPSIEMSSAWAQHVTKMVARRGAILPQ
DISVTPTGTPIPPPEERNKLWMVEAEISPEMMKRKKKKKKRRKEVRPAGPAADEGNPAYH
RREFGPSAVPRLPKLPGHRSLVANLWEQQRQQQEEQDMLPGAFPEFRPSCPLPYQDRYGG
LGYLRNKPSSLPLANPLTLRDSMQGDLSHFQQSSWQPKGVFRHLGQEASMMDVGRTAVVP
RADGRRGVQIHSRTNLMDAELLDADSDF
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:10835429
1GPR0005Galpha-i2-Danio rerio-2
2GPR0298Galpha-i2-Danio rerio-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory