| Details: |
| NAME |
ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2A(Adrenoceptor)_Brachydanio rerio |
| DESCRIPTION |
Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha(2A)AR). |
| SPECIES |
Danio rerio |
COMMON NAME |
Zebrafish |
NCBI Taxonomy |
7955 |
| GENE |
adra2a |
| SEQUENCE |
MICGANATNGTNATKEYTLLVALPLSIAVGLLILLIIFGNVLVIIAVFTSRALRAPQNLF
LVSLASADILVATLVMPFSLANELMGMWTFGGVWCEIYLALDVLFCTASITHLCAISLDR
YWSITQAIEYNLKRTPQRIKRIIFIVWIIAAVISCPPLITMKKSEGDICDINKEKWYIVS
SCIGSFFLPCIIMVLVYIRIYQIAKKRTRAPPGDHRKNEVGKKENDPHEKLNGIQNAEPD
DKDEINGVDMEESSSSDHKVSNPCSLKKKSSKGKTKLSQIKPGDGDKTEACQTTKASRWK
GRQNREKRFTFVLAVVIGVFVICWFPFFFTYTFTAFCDCCVPETLFKFFFWFGYCNSSLN
PIIYTIFNNDFRRSFKKILCRRDKRRVV
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HETERODIMER INFORMATION |
Forms heterodimers with B1 Adrenoceptors. Heterodimerization results in altered ligand binding and internalization of the receptor
|
METHOD |
Immunoprecipitation
|
REFERENCES |
12529373
|
| Scaffold: |
| TYPE |
14-3-3 ksi
|
REFERENCES |
10224112
|
| TYPE |
Spinophilin/neurabin II
|
REFERENCES |
11154706
|
| Coupling with G-proteins: |
| Family:Gi/o |
REFERENCES: | 8662784 | | 1 | GPR0005 | Galpha-i2-Danio rerio-2 | | 2 | GPR0298 | Galpha-i2-Danio rerio-1 |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
