gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0250 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-t
TYPE Galpha-t2

Cross References:
UniProt P19087 EMBL D10384 | Z18859 | AF493909 | BC000233
InterPro IPR001019 | IPR001408 | IPR011025
PRODOM PD000281
GENEID 2780 MIM 139340
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-t2-Homo sapiens
DESCRIPTION Guanine nucleotide-binding protein G(t) subunit alpha-2 (Transducinalpha-2 chain).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
POST TRANSLATION MODIFICATIONS null GENE GNAT2 | GNATC
SEQUENCE 
MGSGASAEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDG
YSPEECLEFKAIIYGNVLQSILAIIRAMTTLGIDYAEPSCADDGRQLNNLADSIEEGTMP
PELVEVIRRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRSRVK
TTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEV
NRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYDDAG
NYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0486Phosphodiesterase-6-Homo sapiens-1Stimulation15251227 | 15988071 | 14699118
2EFF0487Phosphodiesterase-6-Homo sapiens-2Stimulation15251227 | 15988071 | 14699118
3EFF0488Phosphodiesterase-6-Homo sapiens-3Stimulation15251227 | 15988071 | 14699118
4EFF0489Phosphodiesterase-6-Homo sapiens-4Stimulation15251227 | 15988071 | 14699118
5EFF0490Phosphodiesterase-6-Homo sapiens-5Stimulation15251227 | 15988071 | 14699118
6EFF0491Phosphodiesterase-6-Homo sapiens-6Stimulation15251227 | 15988071 | 14699118

Coupling with GPCRs:
1GPCR1938OPSIN/RHODOPSIN FAMILY_Blue opsin_Homo sapiens3867351
2GPCR2738FRIZZLED_Frizzled-2_Homo sapiens11563835
3GPCR1970OPSIN/RHODOPSIN FAMILY_Green-sensitive opsin_Homo sapiens3867351
4GPCR2008OPSIN/RHODOPSIN FAMILY_Opsin 3_Homo sapiens3867351
5GPCR2010OPSIN/RHODOPSIN FAMILY_Opsin 4_Homo sapiens3867351
6GPCR2058OPSIN/RHODOPSIN FAMILY_Photopigment apoprotein _Homo sapiens3867351
7GPCR2097OPSIN/RHODOPSIN FAMILY_Red-sensitive opsin _Homo sapiens3867351
8GPCR2226OPSIN/RHODOPSIN FAMILY_Rhodopsin (Opsin 2)_Homo sapiens3867351
9GPCR2348OPSIN/RHODOPSIN FAMILY_Visual pigment-like peropsin_Homo sapiens3867351



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