gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0491 ::
FAMILY Phosphodiesterases
SUBFAMILY Rhodopsin-sensitive cGMP-specific PDEases
TYPE Phosphodiesterase 6

Cross References:
UniProt Q13956 | Q52LY7 EMBL D45399 | BC069774 | BC069800 | BC093738 | BC093740
InterPro IPR006952
GENEID 5149 MIM 601190 | 610024
PFAM PF04868

Details:
NAME Phosphodiesterase-6-Homo sapiens-6
DESCRIPTION Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterasesubunit gamma (EC 3.1.4.17) (GMP-PDE gamma).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PDE6H
SEQUENCE 
MSDNTTLPAPASNQGPTTPRKGPPKFKQRQTRQFKSKPPKKGVKGFGDDIPGMEGLGTDI
TVICPWEAFSHLELHELAQFGII
 FRAGMENT NO
FUNCTION Participates in processes of transmission ands amplification of the visual signal
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15988071 | 14699118
1GPR0247Galpha-t1-Homo sapiens
2GPR0250Galpha-t2-Homo sapiens
3GPR0279Galpha-t-Homo sapiens

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