gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2738 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY FRIZZLED
SUBFAMILY Frizzled-2

Cross References:
UniProt Q14332 | Q0VG82 EMBL L37882 | AB017364 | BC113402 | BC113404
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB fzd2_human
GENEID 2535 MIM 600667
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME FRIZZLED_Frizzled-2_Homo sapiens
DESCRIPTION Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE FZD2
SEQUENCE
MRPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNL
LGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQG
CEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGAGGTP
GGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEE
TRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVL
QERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKW
GHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPL
FVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACY
FYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIW
SGKTLHSWRKFYTRLTNSRHGETTV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:11563835
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1
Family:Gi/o REFERENCES:11563835
4GPR0247Galpha-t1-Homo sapiens
5GPR0250Galpha-t2-Homo sapiens
6GPR0279Galpha-t-Homo sapiens


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory