gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0490 ::
FAMILY Phosphodiesterases
SUBFAMILY Rhodopsin-sensitive cGMP-specific PDEases
TYPE Phosphodiesterase 6

Cross References:
UniProt P35913 | Q9BWH5 EMBL S41458 | X66142 | X62692 | X62693 | X62694 | X62695 | X90587 | X90588 | X90589 | X90590 | BC000249
InterPro IPR003018 | IPR003607 | IPR002073
MIM 163500 | 180072 | 268000
PRINTS PR00387 PFAM PF01590 | PF00233

Details:
NAME Phosphodiesterase-6-Homo sapiens-5
DESCRIPTION Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit betaprecursor (EC 3.1.4.35) (GMP-PDE beta).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PDE6B | PDEB
SEQUENCE
MSLSEEQARSFLDQNPDFARQYFGKKLSPENVGRGCEDGCPPDCDSLRDLCQVEESTALL
ELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSVLE
DCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLATPI
MNGKDVVAVIMAVNKLNGPFFTSEDEDVFLKYLNFATLYLKIYHLSYLHNCETRRGQVLL
WSANKVFEELTDIER
FRAGMENT NO
FUNCTION This protein participates in processes of transmissions and amplification of the visual signal
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15988071 | 14699118
1GPR0247Galpha-t1-Homo sapiens
2GPR0250Galpha-t2-Homo sapiens
3GPR0279Galpha-t-Homo sapiens


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athina University of Athens
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Biophysics
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Laboratory