gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0243 ::
CLASS Galpha
FAMILY Gq/11
SUBFAMILY Galpha-q
TYPE Galpha-q

Cross References:
UniProt P38410 EMBL L05540 | U10502
InterPro IPR001019 | IPR000654 | IPR011025
PRODOM PD000281
PRINTS PR00318 | PR00442 PFAM PF00503

Details:
NAME Galpha-q-Xenopus laevis
DESCRIPTION Guanine nucleotide-binding protein G(q) subunit alpha (Guaninenucleotide-binding protein alpha-q).
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
POST TRANSLATION MODIFICATIONS null GENE gnaq
SEQUENCE 
MACCLSEEAEEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSG
YSDEDKRGFTKLVYQNIFSAMQAMIRAMETLKIPYKYEHNKGHALLVREVDVEKVASFEN
PYVDAIKYLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRIATHGYLPTQQDVLRVRVPT
TGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNEN
RMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAR
EFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0298Caveolin-1-Xenopus laevisGq Binds Caveolin to Concentrate in Caveolae16182515 | 11251080
2EFF0407Kir 3.1(GIRK1)-Xenopus laevis-1Inhibition12661754
3EFF0408Kir 3.1(GIRK1)-Xenopus laevis-2Inhibition12661754
4EFF0441LARG RhoGEF-Xenopus laevisStimulation (indirect activation of Rho)15251227 | 12024019
5EFF1382Tubulin-Xenopus laevis-1Potentiates receptor-induced PLC-beta activation16182515
6EFF1384Tubulin-Xenopus laevis-11Potentiates receptor-induced PLC-beta activation16182515
7EFF1385Tubulin-Xenopus laevis-12Potentiates receptor-induced PLC-beta activation16182515
8EFF1386Tubulin-Xenopus laevis-13Potentiates receptor-induced PLC-beta activation16182515
9EFF1387Tubulin-Xenopus laevis-14Potentiates receptor-induced PLC-beta activation16182515
10EFF1388Tubulin-Xenopus laevis-15Potentiates receptor-induced PLC-beta activation16182515
11EFF1389Tubulin-Xenopus laevis-16Potentiates receptor-induced PLC-beta activation16182515
12EFF1390Tubulin-Xenopus laevis-17Potentiates receptor-induced PLC-beta activation16182515
13EFF1391Tubulin-Xenopus laevis-18Potentiates receptor-induced PLC-beta activation16182515
14EFF1392Tubulin-Xenopus laevis-19Potentiates receptor-induced PLC-beta activation16182515
15EFF1393Tubulin-Xenopus laevis-2Potentiates receptor-induced PLC-beta activation16182515
16EFF1394Tubulin-Xenopus laevis-20Potentiates receptor-induced PLC-beta activation16182515
17EFF1395Tubulin-Xenopus laevis-21Potentiates receptor-induced PLC-beta activation16182515
18EFF1396Tubulin-Xenopus laevis-22Potentiates receptor-induced PLC-beta activation16182515
19EFF1397Tubulin-Xenopus laevis-23Potentiates receptor-induced PLC-beta activation16182515
20EFF1398Tubulin-Xenopus laevis-24Potentiates receptor-induced PLC-beta activation16182515
21EFF1399Tubulin-Xenopus laevis-25Potentiates receptor-induced PLC-beta activation16182515
22EFF1400Tubulin-Xenopus laevis-26Potentiates receptor-induced PLC-beta activation16182515
23EFF1401Tubulin-Xenopus laevis-27Potentiates receptor-induced PLC-beta activation16182515
24EFF1402Tubulin-Xenopus laevis-28Potentiates receptor-induced PLC-beta activation16182515
25EFF1403Tubulin-Xenopus laevis-10Potentiates receptor-induced PLC-beta activation16182515
26EFF1404Tubulin-Xenopus laevis-3Potentiates receptor-induced PLC-beta activation16182515
27EFF1405Tubulin-Xenopus laevis-9Potentiates receptor-induced PLC-beta activation16182515
28EFF1406Tubulin-Xenopus laevis-4Potentiates receptor-induced PLC-beta activation16182515
29EFF1407Tubulin-Xenopus laevis-5Potentiates receptor-induced PLC-beta activation16182515
30EFF1408Tubulin-Xenopus laevis-6Potentiates receptor-induced PLC-beta activation16182515
31EFF1409Tubulin-Xenopus laevis-7Potentiates receptor-induced PLC-beta activation16182515
32EFF1410Tubulin-Xenopus laevis-8Potentiates receptor-induced PLC-beta activation16182515

Coupling with GPCRs:
1GPCR0410ANGIOTENSIN RECEPTOR_AT1_Xenopus laevis-18865167
2GPCR0415ANGIOTENSIN RECEPTOR_AT1_Xenopus laevis-28865167
3GPCR0736CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK1_Xenopus laevis8503909
4GPCR2729FRIZZLED_Frizzled-1_Xenopus laevis11563835
5GPCR2741FRIZZLED_Frizzled-2_Xenopus laevis11563835
6GPCR1017LYSOPHOSPHOLIPID RECEPTOR_LPA3_Xenopus laevis12215548
7GPCR0876GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Xenopus laevis1516719
8GPCR2457PROTEASE-ACTIVATED RECEPTOR_PAR1_Xenopus laevis10644723
9GPCR1252NEUROPEPTIDE Y RECEPTOR_Y1_Xenopus laevis1321422



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