gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0120 ::
CLASS Galpha
FAMILY Gs
SUBFAMILY Galpha-s
TYPE Galpha-s

Cross References:
UniProt P63091 | P04895 | Q12927 EMBL Z12168
InterPro IPR001019 | IPR000367 | IPR011025
PRODOM PD000281
PRINTS PR00318 | PR00443 PFAM PF00503

Details:
NAME Galpha-s-Canis familiaris
DESCRIPTION Guanine nucleotide-binding protein G(s) subunit alpha (Adenylatecyclase-stimulating G alpha protein).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
POST TRANSLATION MODIFICATIONS null GENE GNAS | GNAS1
SEQUENCE 
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM
RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA
NPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD
KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK
VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY
PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0028Adenylate cyclase-5-Canis familiarisStimulation15251227 | 15922020 | 14993377 | 11376933
2EFF0038Adenylate cyclase-6-Canis familiarisStimulation15251227 | 15922020 | 14993377 | 11376933
3EFF1010Tubulin-Canis familiaris-1Stimulation of GTPase activity10224115 | 15251227 | 16380086
4EFF1011Tubulin-Canis familiaris-2Stimulation of GTPase activity10224115 | 15251227 | 16380086

Coupling with GPCRs:
1GPCR0180ADENOSINE RECEPTOR_A2A_Canis familiaris1662665
2GPCR0313ADRENOCEPTOR (B-ADRENOCEPTOR)_B1(Adrenoceptor)_Canis familiaris2825170
3GPCR0364ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Canis familiaris-13041227
4GPCR0380ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Canis familiaris-23041227
5GPCR0396ADRENOCEPTOR (B-ADRENOCEPTOR)_B3(Adrenoceptor)_Canis familiaris2570461
6GPCR2426PROSTANOID RECEPTOR_EP2_Canis familiaris7910583
7GPCR0974HISTAMINE RECEPTOR_H2_Canis familiaris1703298
8GPCR0875GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Canis familiaris1516719
9GPCR1173MELANOCORTIN RECEPTOR_MC1_Canis familiaris1516719
10GPCR0880GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Canis familiaris8552586
11GPCR2569VASOPRESSIN AND OXYTOCIN RECEPTOR_V2_Canis familiaris1534150



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