gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0028 ::
FAMILY Cyclases
SUBFAMILY Adenylate cyclases
TYPE Adenylate cyclase 5

Cross References:
UniProt P30803 EMBL M88649 | M97886
InterPro IPR001054 | IPR009398 PDB 1AZS | 1CJK | 1CJT | 1CJU | 1CJV | 1CS4 | 1CUL | 1TL7 | 1U0H | 2GVD | 2GVZ
PFAM PF06327 | PF00211

Details:
NAME Adenylate cyclase-5-Canis familiaris
DESCRIPTION Adenylate cyclase type 5 (EC 4.6.1.1) (Adenylate cyclase type V) (ATPpyrophosphate-lyase 5) (Adenylyl cyclase 5) (Ca(2+)-inhibitableadenylyl cyclase).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE ADCY5
SEQUENCE
MSGPRSASPPGCAATRGGPEHRAAWGEAEARANGHPHAAGGATRGCSKKPGGAVTPQLQQ
QQQQQQHEQQHEQQQHEQQQHVQQQQRLAKRWRGDDDPPLGGDDPLAGGFGFSFRSRSAW
QERGGDDCGRGSRRRRRGAAGGGSSRAPPAGGGGGPAAAGGAEVRPRSVELGLDERRGRG
RAEPEPEAEAGAPGGDRGARDGDGPAGPGACCRALLQIFRSKKFPSDKLERLYQRYFFRL
NQSSLTMLMAVLVLV
FRAGMENT NO
FUNCTION This is a membrane-bound, calcium-inhibitable adenylyls cyclase
Interacting with G-proteins:
Family:Gi/o REFERENCES:15251227 | 15922020 | 14993377 | 11376933
1GPR0223Galpha-i2-Canis familiaris
Family:Gs REFERENCES:15251227 | 15922020 | 14993377 | 11376933
2GPR0120Galpha-s-Canis familiaris
Family:Gbeta REFERENCES:15251227 | 15922020 | 14993377 | 11376933
3GPR0146Gbeta-1-Canis familiaris
4GPR0159Gbeta-3-Canis familiaris
Family:Ggamma REFERENCES:15251227 | 15922020 | 14993377 | 11376933
5GPR0177Ggamma-t1-Canis familiaris


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athina University of Athens
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