gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0875 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GLYCOPROTEIN HORMONE RECEPTOR
SUBFAMILY LSH RECEPTOR

Cross References:
UniProt Q95MF7 EMBL AF389885
InterPro IPR000276 | IPR002131 GPCRDB q95mf7_canfa
PRINTS PR00373 | PR00237 PFAM PF00001

Details:
NAME GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Canis familiaris
DESCRIPTION Luteinizing hormone receptor .
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE LHR
SEQUENCE
DNGFCSPKILRCAPEPDAFNPCEDIMGYNFLRVLIWLINILAIVGNVTVLFVLLTSRYKL
TVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCSAAGFFTVFSSE
LSVYTLTVITLERWHTITYALQLDQKLRLRHAIPIMLGGWLFSTLIAMLPLVGVSNYMKV
SICLPMDVETTLSQVYILTILILNVVAFIIICACYIKIYFAVQNPELMATNKDTKIAKKM
AVLIFTDFTCMAPISFFAISAAFKMPLITVTNSKVLLVLFYPVNSCANPFLYA
FRAGMENT YES

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 11108263

Scaffold:
TYPE GIPC( GAIP-interacting protein) REFERENCES 14507927
TYPE NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein) REFERENCES 14507927
TYPE p38JAB1 REFERENCES 10788448

Coupling with G-proteins:
Family:Gi/o REFERENCES:1516719
1GPR0223Galpha-i2-Canis familiaris
Family:Gq/11 REFERENCES:1516719
2GPR0233Galpha-q-Canis familiaris
Family:Gs REFERENCES:1516719
3GPR0120Galpha-s-Canis familiaris


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athina University of Athens
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