gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0974 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY HISTAMINE RECEPTOR
SUBFAMILY H2

Cross References:
UniProt P17124 EMBL M32701
InterPro IPR000276 | IPR000503 GPCRDB hrh2_canfa
GENEID 403812
PRINTS PR00237 | PR00531 PFAM PF00001

Details:
NAME HISTAMINE RECEPTOR_H2_Canis familiaris
DESCRIPTION Histamine H2 receptor (H2R) (Gastric receptor I).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
GENE HRH2
SEQUENCE
MISNGTGSSFCLDSPPCRITVSVVLTVLILITIAGNVVVCLAVGLNRRLRSLTNCFIVSL
AITDLLLGLLVLPFSAFYQLSCRWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLITPVRVAVSLVLIWVISITLSFLSIHLGWNSRNETSSFNHTIPKCKVQVNL
VYGLVDGLVTFYLPLLVMCITYYRIFKIARDQAKRIHHMGSWKAATIGEHKATVTLAAVM
GAFIICWFPYFTVFVYRGLKGDDAINEAFEAVVLWLGYANSALNPILYATLNRDFRTAYQ
QLFRCRPASHNAQETSLRSNSSQLARNQSREPMRQEEKPLKLQVWSGTEVTAPRGATDR
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 9202162

Coupling with G-proteins:
Family:Gs REFERENCES:1703298
1GPR0120Galpha-s-Canis familiaris


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory