gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0244 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-t
TYPE Galpha-t

Cross References:
UniProt P38407 | Q2T9I4 EMBL L07771 | BC111509
InterPro IPR001019 | IPR001408 | IPR011025
PRODOM PD000281
GENEID 399262
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-t-Xenopus laevis
DESCRIPTION Guanine nucleotide-binding protein G(t) subunit alpha (Transducinalpha chain).
SPECIES Xenopus laevis COMMON NAME African clawed frog NCBI Taxonomy 8355
POST TRANSLATION MODIFICATIONS null GENE gnat
SEQUENCE
MGAGASAEEKHSRELEKKLKEDADKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSVE
ECLEFIAIIYGNTLQSMIAIVKAMNTLNIQFGDPARQDDARKLMHLADTIDEGSMPKEMS
DIIGRLWKDTGIQACFDRASEYQLNDSAGYYLNDLDRLVIPGYVPTEQDVLRSRVKTTGI
IETQFGLKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMH
ESLHLFNSICNHRYFATTSIVLFLNKKDVFTEKIKKAHLSICFPDYDGPNTYEDAGNYIK
TQFLELNMRRDVKEIYSHMTCATDTENVKFVFDAVTDIIIKENLKDCGLF
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0512Phosphodiesterase-6-Xenopus laevis-1Stimulation15251227 | 15988071 | 14699118
2EFF0513Phosphodiesterase-6-Xenopus laevis-2Stimulation15251227 | 15988071 | 14699118
3EFF0514Phosphodiesterase-6-Xenopus laevis-3Stimulation15251227 | 15988071 | 14699118
4EFF0515Phosphodiesterase-6-Xenopus laevis-4Stimulation15251227 | 15988071 | 14699118

Coupling with GPCRs:
1GPCR2741FRIZZLED_Frizzled-2_Xenopus laevis11563835
2GPCR2093OPSIN/RHODOPSIN FAMILY_Red-sensitive opsin _Xenopus laevis3867351
3GPCR2125OPSIN/RHODOPSIN FAMILY_Rhodopsin_Xenopus laevis3867351
4GPCR2341OPSIN/RHODOPSIN FAMILY_Violet-sensitive opsin_Xenopus laevis3867351




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athina University of Athens
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Biophysics
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Laboratory