gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2727 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY FRIZZLED
SUBFAMILY Frizzled-1

Cross References:
UniProt P18537 | Q9VUE0 | Q9VUE2 EMBL X54648 | X54649 | X54650 | X54651 | X54648 | X54649 | X54650 | X54652 | X54646 | X54647 | AE014296 | AE014296 | AY051808
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB friz_drome
FlyBase FBgn0001085
GENEID 45307
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME FRIZZLED_Frizzled-1_Drosophila melanogaster
DESCRIPTION Frizzled precursor (Frizzled-1) (dFz1).
SPECIES Drosophila melanogaster COMMON NAME Fruit fly NCBI Taxonomy 7227
GENE fz | CG17697
SEQUENCE
MWRQILFILPTLIQGVQRYDQSPLDASPYYRSGGGLMASSGTELDGLPHHNRCEPITISI
CKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILERP
IPPCRSLCESARVCEKLMKTYNFNWPENLECSKFPVHGGEDLCVAENTTSSASTAATPTR
SVAKVTTRKHQTGVESPHRNIGFVCPVQLKTPLGMGYELKVGGKDLHDCGAPCHAMFFPE
RERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGL
GAGDSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAF
AWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTH
SLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRTDKLERLMLRIGFFSGLFI
LPAVGLLGCLFYEYYNFDEWMIQWHRDICKPFSIPCPAARAPGSPEARPIFQIFMVKYLC
SMLVGVTSSVWLYSSKTMVSWRNFVERLQGKEPRTRAQAYV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11563835
1GPR0019Galpha-o-Drosophila melanogaster
2GPR0230Galpha-i-Drosophila melanogaster
Family:Gq/11 REFERENCES:11563835
3GPR0234Galpha-q-Drosophila melanogaster


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory