gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0019 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-o
TYPE Galpha-o

Cross References:
UniProt P16378 | A4UZB6 | A4UZC1 | P16377 | P16707 | Q540V8 | Q9V5L5 | Q9V5L6 EMBL M86660 | M29602 | M31203 | M29601 | M31198 | M31199 | M31200 | M31201 | M31202 | M30151 | M30152 | M31129 | M29731 | M29732 | AE013599 | AE013599 | AE013599 | AE013599 | AE013599 | AE013599 | AE013599 | AE013599 | AY121631
InterPro IPR001019 | IPR001408 | IPR011025
PRODOM PD000281 FlyBase FBgn0001122
GENEID 36104
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-o-Drosophila melanogaster
DESCRIPTION Guanine nucleotide-binding protein G(o) subunit alpha 47A.
SPECIES Drosophila melanogaster COMMON NAME Fruit fly NCBI Taxonomy 7227
POST TRANSLATION MODIFICATIONS null GENE G-oalpha47A | G-oa47A | CG2204
SEQUENCE
MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESG
FTAEDFKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPF
SEELLAAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRV
KTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDET
TNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEA
AAYIQAQFEAKNKSTSKEIYCHMTCATDTNNIQFVFDAVTDVIIANNLRGCGLY
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0847Src tyrosine kinase-Drosophila melanogaster-1Stimulation11007482 | 15251227 | 12209124
2EFF0848Src tyrosine kinase-Drosophila melanogaster-2Stimulation11007482 | 15251227 | 12209124
3EFF1041Tubulin-Drosophila melanogaster-1Stimulation of GTPase activity10224115 | 15251227 | 16380086
4EFF1042Tubulin-Drosophila melanogaster-10Stimulation of GTPase activity10224115 | 15251227 | 16380086
5EFF1045Tubulin-Drosophila melanogaster-13Stimulation of GTPase activity10224115 | 15251227 | 16380086
6EFF1047Tubulin-Drosophila melanogaster-14Stimulation of GTPase activity10224115 | 15251227 | 16380086
7EFF1050Tubulin-Drosophila melanogaster-12Stimulation of GTPase activity10224115 | 15251227 | 16380086
8EFF1051Tubulin-Drosophila melanogaster-11Stimulation of GTPase activity10224115 | 15251227 | 16380086
9EFF1052Tubulin-Drosophila melanogaster-2Stimulation of GTPase activity10224115 | 15251227 | 16380086
10EFF1053Tubulin-Drosophila melanogaster-3Stimulation of GTPase activity10224115 | 15251227 | 16380086
11EFF1054Tubulin-Drosophila melanogaster-4Stimulation of GTPase activity10224115 | 15251227 | 16380086
12EFF1055Tubulin-Drosophila melanogaster-5Stimulation of GTPase activity10224115 | 15251227 | 16380086
13EFF1056Tubulin-Drosophila melanogaster-6Stimulation of GTPase activity10224115 | 15251227 | 16380086
14EFF1057Tubulin-Drosophila melanogaster-7Stimulation of GTPase activity10224115 | 15251227 | 16380086
15EFF1058Tubulin-Drosophila melanogaster-8Stimulation of GTPase activity10224115 | 15251227 | 16380086
16EFF1059Tubulin-Drosophila melanogaster-9Stimulation of GTPase activity10224115 | 15251227 | 16380086

Coupling with GPCRs:
1GPCR0406ALLATOSTATIN RECEPTOR_Allatostatin_Drosophila melanogaster-110545101
2GPCR0407ALLATOSTATIN RECEPTOR_Allatostatin_Drosophila melanogaster-210545101
3GPCR0791DOPAMINE RECEPTOR_D2_Drosophila melanogaster2974511
4GPCR2727FRIZZLED_Frizzled-1_Drosophila melanogaster11563835
5GPCR2800SMOOTHENED_smoothened_Drosophila melanogaster-210835429
6GPCR2804SMOOTHENED_smoothened_Drosophila melanogaster-110835429
7GPCR1262NEUROPEPTIDE Y RECEPTOR_Y4_Drosophila melanogaster7592911




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