gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0230 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-i
TYPE Galpha-i

Cross References:
UniProt P20353 | Q9VS04 EMBL M23093 | M23094 | AE014296 | AY051670
InterPro IPR001019 | IPR001408 | IPR011025
PRODOM PD000281 FlyBase FBgn0001104
GENEID 38765
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-i-Drosophila melanogaster
DESCRIPTION Guanine nucleotide-binding protein G(i) subunit alpha 65A.
SPECIES Drosophila melanogaster COMMON NAME Fruit fly NCBI Taxonomy 7227
POST TRANSLATION MODIFICATIONS null GENE G-ialpha65A | G-OA65C | CG10060
SEQUENCE 
MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDT
GYSQEECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADEGIL
LPEIVLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRV
KTTGIIETHFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEE
MNRMIESLKLFDSICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEA
ANYIRMKFENLNKRKDQKEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGLF
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0639Rac-Drosophila melanogaster-2Stimulation11099498
2EFF0640Rac-Drosophila melanogaster-1Stimulation11099498
3EFF0847Src tyrosine kinase-Drosophila melanogaster-1Stimulation11007482 | 15251227 | 12209124
4EFF0848Src tyrosine kinase-Drosophila melanogaster-2Stimulation11007482 | 15251227 | 12209124
5EFF1041Tubulin-Drosophila melanogaster-1Stimulation of GTPase activity10224115 | 15251227 | 16380086
6EFF1042Tubulin-Drosophila melanogaster-10Stimulation of GTPase activity10224115 | 15251227 | 16380086
7EFF1045Tubulin-Drosophila melanogaster-13Stimulation of GTPase activity10224115 | 15251227 | 16380086
8EFF1047Tubulin-Drosophila melanogaster-14Stimulation of GTPase activity10224115 | 15251227 | 16380086
9EFF1050Tubulin-Drosophila melanogaster-12Stimulation of GTPase activity10224115 | 15251227 | 16380086
10EFF1051Tubulin-Drosophila melanogaster-11Stimulation of GTPase activity10224115 | 15251227 | 16380086
11EFF1052Tubulin-Drosophila melanogaster-2Stimulation of GTPase activity10224115 | 15251227 | 16380086
12EFF1053Tubulin-Drosophila melanogaster-3Stimulation of GTPase activity10224115 | 15251227 | 16380086
13EFF1054Tubulin-Drosophila melanogaster-4Stimulation of GTPase activity10224115 | 15251227 | 16380086
14EFF1055Tubulin-Drosophila melanogaster-5Stimulation of GTPase activity10224115 | 15251227 | 16380086
15EFF1056Tubulin-Drosophila melanogaster-6Stimulation of GTPase activity10224115 | 15251227 | 16380086
16EFF1057Tubulin-Drosophila melanogaster-7Stimulation of GTPase activity10224115 | 15251227 | 16380086
17EFF1058Tubulin-Drosophila melanogaster-8Stimulation of GTPase activity10224115 | 15251227 | 16380086
18EFF1059Tubulin-Drosophila melanogaster-9Stimulation of GTPase activity10224115 | 15251227 | 16380086

Coupling with GPCRs:
1GPCR0406ALLATOSTATIN RECEPTOR_Allatostatin_Drosophila melanogaster-110545101
2GPCR0407ALLATOSTATIN RECEPTOR_Allatostatin_Drosophila melanogaster-210545101
3GPCR0791DOPAMINE RECEPTOR_D2_Drosophila melanogaster2974511
4GPCR2727FRIZZLED_Frizzled-1_Drosophila melanogaster11563835
5GPCR2800SMOOTHENED_smoothened_Drosophila melanogaster-210835429
6GPCR2804SMOOTHENED_smoothened_Drosophila melanogaster-110835429
7GPCR1262NEUROPEPTIDE Y RECEPTOR_Y4_Drosophila melanogaster7592911



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