gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0234 ::
CLASS Galpha
FAMILY Gq/11
SUBFAMILY Galpha-q
TYPE Galpha-q

Cross References:
UniProt P23625 | P54400 | Q29QX1 | Q540Y7 | Q9I7C8 | Q9V6E2 EMBL M58016 | U31092 | AE013599 | AE013599 | AY118511 | BT024269
InterPro IPR001019 | IPR000654 | IPR011025
PRODOM PD000281 FlyBase FBgn0004435
GENEID 36384
PRINTS PR00318 | PR00442 PFAM PF00503

Details:
NAME Galpha-q-Drosophila melanogaster
DESCRIPTION Guanine nucleotide-binding protein G(q) subunit alpha (Guaninenucleotide-binding protein alpha-q) (dGQalpha).
SPECIES Drosophila melanogaster COMMON NAME Fruit fly NCBI Taxonomy 7227
POST TRANSLATION MODIFICATIONS null GENE Galpha49B | dgq | G-A49B | CG17759
SEQUENCE 
MECCLSEEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSG
YSDEDKRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTTFED
PYLNAIKTLWDDAGIQECYDRRREYQLTDSAKYYLSDLARIEQADYLPTEQDILRARVPT
TGILEYPFDLDGIVFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESDNEN
RMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPKQDHAAAK
QFVLKKYLACNPDPERQCYSHFTTATDTENIKLVFCAVKDTIMQNALKEFNLG
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0873Synembryn(Ric8a)-Drosophila melanogasterStimulates Gqa activation and steady-state GTPase activity in vitro16182515 | 12509430
2EFF1041Tubulin-Drosophila melanogaster-1Potentiates receptor-induced PLC-beta activation16182515
3EFF1042Tubulin-Drosophila melanogaster-10Potentiates receptor-induced PLC-beta activation16182515
4EFF1045Tubulin-Drosophila melanogaster-13Potentiates receptor-induced PLC-beta activation16182515
5EFF1047Tubulin-Drosophila melanogaster-14Potentiates receptor-induced PLC-beta activation16182515
6EFF1050Tubulin-Drosophila melanogaster-12Potentiates receptor-induced PLC-beta activation16182515
7EFF1051Tubulin-Drosophila melanogaster-11Potentiates receptor-induced PLC-beta activation16182515
8EFF1052Tubulin-Drosophila melanogaster-2Potentiates receptor-induced PLC-beta activation16182515
9EFF1053Tubulin-Drosophila melanogaster-3Potentiates receptor-induced PLC-beta activation16182515
10EFF1054Tubulin-Drosophila melanogaster-4Potentiates receptor-induced PLC-beta activation16182515
11EFF1055Tubulin-Drosophila melanogaster-5Potentiates receptor-induced PLC-beta activation16182515
12EFF1056Tubulin-Drosophila melanogaster-6Potentiates receptor-induced PLC-beta activation16182515
13EFF1057Tubulin-Drosophila melanogaster-7Potentiates receptor-induced PLC-beta activation16182515
14EFF1058Tubulin-Drosophila melanogaster-8Potentiates receptor-induced PLC-beta activation16182515
15EFF1059Tubulin-Drosophila melanogaster-9Potentiates receptor-induced PLC-beta activation16182515

Coupling with GPCRs:
1GPCR00675-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2A_Drosophila melanogaster1765383
2GPCR00785-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2B_Drosophila melanogaster8786115
3GPCR2727FRIZZLED_Frizzled-1_Drosophila melanogaster11563835
4GPCR2740FRIZZLED_Frizzled-2_Drosophila melanogaster11563835



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