| Details: |
| NAME |
GRK2-Homo sapiens |
| DESCRIPTION |
Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G-protein coupled receptor kinase 2). |
| SPECIES |
Homo sapiens |
COMMON NAME |
Human |
NCBI Taxonomy |
9606 |
| GENE |
ADRBK1 | BARK | BARK1 | GRK2 |
| SEQUENCE |
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
QKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAC
SHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIV
|
FRAGMENT |
NO
|
| FUNCTION |
Specifically phosphorylates the agonist-occupied form ofs the beta-adrenergic and closely related receptors, probablys inducing a desensitization of them |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
