gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0146 ::
CLASS Gbeta
FAMILY Gbeta
SUBFAMILY Gbeta
TYPE Gbeta-1

Cross References:
UniProt P62872 | P04697 | P04901 EMBL Z75134
InterPro IPR001632 | IPR015943 | IPR001680
PRODOM PD000018
GENEID 403912
PRINTS PR00319 | PR00320 PFAM PF00400

Details:
NAME Gbeta-1-Canis familiaris
DESCRIPTION Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1(Transducin beta chain 1).
SPECIES Canis familiaris COMMON NAME Dog NCBI Taxonomy 9615
POST TRANSLATION MODIFICATIONS null GENE GNB1
SEQUENCE 
MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYA
MHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNI
CSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTF
TGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNA
FATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL
KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as a modulator or transducer in various transmembranes signaling systems
Effectors:
1EFF0028Adenylate cyclase-5-Canis familiarisInhibition15251227 | 15922020 | 14993377 | 11376933
2EFF0038Adenylate cyclase-6-Canis familiarisInhibition15251227 | 15922020 | 14993377 | 11376933
3EFF0080ATP-sensitive inward rectifier potassium channel-11-Canis familiarisStimulation15251227 | 10990455
4EFF0619Rac-Canis familiarisStimulation,Recruitment to plasma membrane11099498 | 15251227
5EFF0727Rho-Canis familiarisRecruitment to plasma membrane15251227
6EFF1010Tubulin-Canis familiaris-1Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086
7EFF1011Tubulin-Canis familiaris-2Increased GTPase activity15251227 | 14671004 | 12807915 | 17705289 | 16380086

Coupling with GPCRs:
No information



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