gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0045 ::
CLASS Galpha
FAMILY Gq/11
SUBFAMILY Galpha-15/16
TYPE Galpha-15

Cross References:
UniProt O88302 EMBL AB015308
InterPro IPR001019 | IPR000654 | IPR011025
PRODOM PD000281
GENEID 89788
PRINTS PR00318 | PR00442 PFAM PF00503

Details:
NAME Galpha-15-Rattus norvegicus
DESCRIPTION Guanine nucleotide-binding protein alpha-15 subunit (G alpha-15).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
POST TRANSLATION MODIFICATIONS null GENE Gna15
SEQUENCE 
MARSLTWGCCPWCLTEEEKTAARIDQEINKILLEQKKQERGELKLLLLGPGESGKSTFIK
QMRIIHGAGYSEEDRRAFRLLVYQNIFVSMQAMIEAMDRLQIPFSRPDSKQHASLVMTQD
PYKVSSFEKPYAVAMQYLWRDAGIRACYERRREFHLLDSAVYYLSHLERIAEDDYIPTAQ
DVLRSRMPTTGINEYCFSVQKTKLRIVDAGGQKSERKKWIHCFENVIALIYLASLSEYDQ
CLEENSQENRMKESLALFSTILELPWFKSTSVILFLNKTDILEDKIHTSHLASYFPSFQG
PRRDAEAAKRFILDMYARVYASCAEPHDGGRKGSRARRLFAHFTCATDTHSVRSVFKDVR
DSVLARYLDEINLL
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0378GRK6-Rattus norvegicus-1Stimulation14654303
2EFF0379GRK6-Rattus norvegicus-2Stimulation14654303
3EFF0380GRK6-Rattus norvegicus-3Stimulation14654303
4EFF0381GRK6-Rattus norvegicus-4Stimulation14654303
5EFF0528Phospholipase C beta-1-Rattus norvegicusStimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
6EFF0538Phospholipase C beta-2-Rattus norvegicus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
7EFF0539Phospholipase C beta-2-Rattus norvegicus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
8EFF0552Phospholipase C beta-3-Rattus norvegicus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
9EFF0553Phospholipase C beta-3-Rattus norvegicus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
10EFF0569Phospholipase C beta-4-Rattus norvegicusStimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
11EFF0881TRP repeat protein-1-Rattus norvegicusG16a co-expression enhances TPR1 interaction with Ras16182515 | 12748287

Coupling with GPCRs:
1GPCR0712CHEMOTACTIC PEPTIDE RECEPTOR_C5A_Rattus norvegicus7870028



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