gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0712 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHEMOTACTIC PEPTIDE RECEPTOR
SUBFAMILY C5A

Cross References:
UniProt P97520 | O09088 EMBL Y09613 | AB003042 | BC078770
InterPro IPR002234 | IPR001274 | IPR000276 GPCRDB c5ar_rat
GENEID 113959
PRINTS PR01104 | PR00426 | PR00237 PFAM PF00001

Details:
NAME CHEMOTACTIC PEPTIDE RECEPTOR_C5A_Rattus norvegicus
DESCRIPTION C5a anaphylatoxin chemotactic receptor (C5a-R) (C5aR) (CD88 antigen).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE C5ar1 | C5r1
SEQUENCE
MDPISNDSSEITYDYSDGTPNPDMPADGVYIPKMEPGDIAALIIYLAVFLVGVTGNALVV
WVTAFEAKRTVNAIWFLNLAVADLLSCLALPILFTSIVKHNHWPFGDQACIVLPSLILLN
MYSSILLLATISADRFLLVFKPIWCQKFRRPGLAWMACGVTWVLALLLTIPSFVFRRIHK
DPYSDSILCNIDYSKGPFFIEKAIAILRLMVGFVLPLLTLNICYTFLLIRTWSRKATRST
KTLKVVMAVVTCFFVFWLPYQVTGVILAWLPRSSSTFQSVERLNSLCVSLAYINCCVNPI
IYVMAGQGFHGRLRRSLPSIIRNVLSEDSLGRDSKSFTRSTMDTSTQKSQAV
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Fluorescence Resonance Energy Transfer (FRET) REFERENCES 12835318

Coupling with G-proteins:
Family:Gq/11 REFERENCES:7870028
1GPR0045Galpha-15-Rattus norvegicus
Family:Gi/o REFERENCES:7887933
2GPR0026Galpha-o-Rattus norvegicus
3GPR0111Galpha-i3-Rattus norvegicus
4GPR0221Galpha-i1-Rattus norvegicus
5GPR0229Galpha-i2-Rattus norvegicus
6GPR0130Galpha-z-Rattus norvegicus


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athina University of Athens
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Biophysics
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