gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::Effector View
Entry 1 of 1 :: EFF0569 ::
FAMILY Phospholipases C
SUBFAMILY Phospholipases C beta
TYPE Phospholipase C beta 4

Cross References:
UniProt Q9QW07 | O88356 | Q9Z0G6 EMBL L15556 | U57836 | AF031370 | AF027571
InterPro IPR000008 | IPR009535 | IPR011992 | IPR015359 | IPR013841 | IPR001192 | IPR000909 | IPR001711
PRODOM PD001202 GENEID 25031
PRINTS PR00390 PFAM PF00168 | PF06631 | PF09279 | PF00388 | PF00387

Details:
NAME Phospholipase C beta-4-Rattus norvegicus
DESCRIPTION 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4(EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-beta-4) (PLC-beta-4).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Plcb4
SEQUENCE
MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVL
ECSLINSIRLAAIPKDPKILAALESVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPE
ITKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTSGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRL
FRAGMENT NO
FUNCTION The production of the second messenger moleculess diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) iss mediated by activated phosphatidylinositol-specific phospholipases C enzymes
Interacting with G-proteins:
Family:Gq/11 REFERENCES:15251227 | 16182515 | 11015615
1GPR0032Galpha-11-Rattus norvegicus
2GPR0045Galpha-15-Rattus norvegicus
3GPR0242Galpha-q-Rattus norvegicus


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