gpDB::GPCR View

gpDB: a database of G-proteins and their interaction with GPCRs

gpDB::GPCR View

Entry 1 of 1 :: GPCR0067 ::

CLASS	CLASS A (RHODOPSIN LIKE)
FAMILY	5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY	5-HT-2A

Cross References:
UniProt	P28285 \| Q0E921 \| Q4QQC9 \| Q5MTE9 \| Q5MTF1 \| Q5MTF2 \| Q5MTF3 \| Q5MTF8	EMBL	Z11489 \| AE013599 \| BT023487 \| AY564785 \| AY564786 \| AY564787 \| AY564788 \| AY564789 \| AY564790 \| AY564791 \| AY564792 \| AY564793 \| AY564794 \| AY564795 \| AY564796 \| AY564797 \| AY564798 \| AY564799 \| AY564800 \| AY564801 \| AY564802 \| AY564803 \| AY564804 \| AY564805 \| AY564806 \| AY564807 \| AY564808 \| AY564809 \| AY564810 \| AY564811 \| AY564812 \| AY564813 \| AY564814 \| AY564815 \| AY564816 \| AY564817 \| AY564818 \| AY564819 \| AY564820 \| AY564821 \| AY564822 \| AY564823 \| AY564824 \| AY564825 \| AY564826 \| AY564827 \| AY564828 \| AY564829 \| AY564830 \| AY564831 \| AY564832 \| AY564833 \| AY564834 \| AY564835 \| AY564836 \| AY564837 \| AY564838 \| AY564839 \| AY564840 \| AY564841 \| AY564842 \| AY564843 \| AY564844 \| AY564845 \| AY564846 \| AY564847 \| AY564848 \| AY564849 \| AY564850 \| AY564851 \| AY564852 \| AY564853 \| AY564854 \| AY564855 \| AY564856 \| AY564857 \| AY564858 \| AY564859 \| AY564860 \| AY564861 \| AY564862 \| AY564863 \| AY564864 \| AY564865 \| AY564866 \| AY564867 \| AY564868 \| AY564869 \| AY564870 \| AY564871 \| AY564872 \| AY564873 \| AY564874 \| AY564875 \| AY564876 \| AY564877 \| AY564878 \| AY564879 \| AY564880 \| AY564881 \| AY564882 \| AY564883 \| AY564884 \| AY564885 \| AY564886 \| AY564887 \| AY564888 \| AY564889 \| AY564890 \| AY564891 \| AY564892 \| AY564893 \| AY564894 \| AY564895 \| AY564896 \| AY564897 \| AY564898 \| AY564899 \| AY564900 \| AY564901 \| AY564902 \| AY564903 \| AY564904 \| AY564905 \| AY564906 \| AY564907 \| AY564908 \| AY564909 \| AY564910 \| AY564911 \| AY564912 \| AY564913 \| AY564914 \| AY564915 \| AY564916 \| AY564917 \| AY564918 \| AY564919 \| AY564920 \| AY564921 \| AY564922 \| AY564925 \| AY564926 \| AY564927 \| AY564928 \| AY564929 \| AY564930 \| AY564931 \| AY564932 \| AY564933 \| AY564934 \| AY564935 \| AY564936 \| AY564937 \| AY564938 \| AY564939 \| AY564940 \| AY564941 \| AY564942 \| AY564943 \| AY564944 \| AY564945 \| AY564946 \| AY564947 \| AY564948 \| AY564949 \| AY564950 \| AY564951 \| AY564952 \| AY564953 \| AY564954 \| AY564955 \| AY564956 \| AY564958 \| AY564959 \| AY564960 \| AY564961 \| AY564962 \| AY564963 \| AY564964 \| AY564965 \| AY564966 \| AY564967 \| AY564968 \| AY564969 \| AY564971 \| AY564972 \| AY564973 \| AY564974 \| AY564975 \| AY564976 \| AY564977 \| AY565171 \| AY565172 \| AY565173 \| AY565174 \| AY565175 \| AY565176 \| AY565177 \| AY565178 \| AY565179 \| AY565180 \| AY565181 \| AY565182 \| AY565183 \| AY565184 \| AY565185 \| AY565186 \| AY565187 \| AY565188 \| AY565189 \| AY565190 \| AY565191 \| AY565192 \| AY565193 \| AY565194 \| AY565195 \| AY565196 \| AY565197 \| AY565198 \| AY565199 \| AY565200 \| AY565201 \| AY565202 \| AY565203 \| AY565204 \| AY565205 \| AY565206 \| AY565207 \| AY565208 \| AY565209 \| AY565210 \| AY565211 \| AY565212 \| AY565213 \| AY565214 \| AY565215 \| AY565216 \| AY565217 \| AY565218 \| AY565219 \| AY565220 \| AY565221 \| AY565222 \| AY565223 \| AY565224 \| AY565225 \| AY565226 \| AY565227 \| AY565228 \| AY565229 \| AY565230 \| AY565231 \| AY565232 \| AY565233 \| AY565234 \| AY565235 \| AY565236 \| AY565237 \| AY565238 \| AY565239 \| AY565240 \| AY565241 \| AY565242 \| AY565243 \| AY565244 \| AY565245 \| AY565246 \| AY565247 \| AY565248 \| AY565249 \| AY565250 \| AY565251 \| AY565252 \| AY565253 \| AY565254 \| AY565255 \| AY565256 \| AY565257 \| AY565258 \| AY565259 \| AY565260 \| AY565261 \| AY565262 \| AY565263 \| AY565264 \| AY565265 \| AY565266 \| AY565267 \| AY565268 \| AY565269 \| AY565270 \| AY565271 \| AY565272 \| AY565273 \| AY565274 \| AY565275 \| AY565276 \| AY565277 \| AY565278 \| AY565279 \| AY565280 \| AY565281 \| AY565282 \| AY565283 \| AY565284 \| AY565285 \| AY565286 \| AY565287 \| AY565288 \| AY565289 \| AY565290 \| AY565291 \| AY565292 \| AY565293 \| AY565294 \| AY565295 \| AY565296 \| AY565297 \| AY565298 \| AY565299 \| AY565300 \| AY565301 \| AY565302 \| AY565303 \| AY565304 \| AY565305 \| AY565306 \| AY565307 \| AY565308 \| AY565309 \| AY565310 \| AY565311 \| AY565312 \| AY565313 \| AY565314 \| AY565315 \| AY565316 \| AY565317 \| AY565318 \| AY565319 \| AY565320 \| AY565321 \| AY565322 \| AY565323 \| AY565324 \| AY565325 \| AY565326 \| AY565327 \| AY565328 \| AY565329 \| AY565330 \| AY565331 \| AY565332 \| AY565333 \| AY565334 \| AY565335 \| AY565336 \| AY565337 \| AY565338 \| AY565339 \| AY565340 \| AY565341 \| AY565342 \| AY565343 \| AY565344 \| AY565345 \| AY565346 \| AY565347 \| AY565348 \| AY565349 \| AY565350 \| AY565351 \| AY565352 \| AY565353 \| AY565354 \| AY565355 \| AY565356 \| AY565357 \| AY565358 \| AY565359 \| AY565360 \| AY565361 \| AY565362 \| AY565363 \| AY565364 \| AY565365 \| AY565366 \| AY565367 \| AY565368
InterPro	IPR000276	GPCRDB	5ht2a_drome
FlyBase	FBgn0004168
GENEID	37196
PRINTS	PR00237	PFAM	PF00001

Details:
NAME	5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2A_Drosophila melanogaster
DESCRIPTION	5-hydroxytryptamine receptor 2A (5-HT receptor) (Serotonin receptor2A).
SPECIES	Drosophila melanogaster	COMMON NAME	Fruit fly	NCBI Taxonomy	7227
GENE	5-HT1A \| 5HT-R2A \| CG16720
SEQUENCE	MAHETSFNDALDYIYIANSMNDRAFLIAEPHPEQPNVDGQDQDDAELEELDDMAVTDDGQ LEDTNNNNNSKRYYSSGKRRADFIGSLALKPPPTDVNTTTTTAGSPLATAALAAAAASAS VAAAAARITAKAAHRALTTKQDATSSPASSPALQLIDMDNNYTNVAVGLGAMLLNDTLLL EGNDSSLFGEMLANRSGQLDLINGTGGLNVTTSKVAEDDFTQLLRMAVTSVLLGLMILVT IIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISQGWILGPELCD IWTSCDVLCCTASILHLVAIAVDRYWAVTNIDYIHSRTSNRVFMMIFCVWTAAVIVSLAP QFGWKDPDYLQRIEQQKCMVSQDVSYQVFATCCTFYVPLLVILALYWKIYQTARKRIHRR RPRPVDAAVNNNQPDGGAATDTKLHRLRLRLGRFSTAKSKTGSAVGVSGPASGGRALGLV DGNSTNTVNTVEDTEFSSSNVDSKSRAGVEAPSTSGNQIATVSHLVALAKQQGKSTAKSS AAVNGMAPSGRQEDDGQRPEHGEQEDREELEDQDEQVGPQPTTATSATTAAGTNESEDQC KANGVEVLEDPQLQQQLEQVQQLQKSVKSGGGGGASTSNATTITSISALSPQTPTSQGVG IAAAAAGPMTAKTSTLTSCNQSHPLCGTANESPSTPEPRSRQPTTPQQQPHQQAHQQQQQ QQQLSSIANPMQKVNKRKETLEAKRERKAAKTLAIITGAFVVCWLPFFVMALTMPLCAAC QISDSVASLFLWLGYFNSTLNPVIYTIFSPEFRQAFKRILFGGHRPVHYRSGKL				FRAGMENT	NO



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Scaffold:
TYPE	JAK2( Janus kinase)			REFERENCES	9169451
TYPE	MUPP1( multiple activated protein kinase 1)			REFERENCES	11150294
TYPE	PSD95( postsynaptic density protein)			REFERENCES	12682061

Coupling with G-proteins:
Family:Gq/11		REFERENCES:	1765383
1	GPR0234	Galpha-q-Drosophila melanogaster


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	University of Athens Faculty of Biology Dept. of Cell Biology and Biophysics	Biophysics & Bioinformatics Laboratory