gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0816 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ENDOTHELIN RECEPTOR
SUBFAMILY ET-A

Cross References:
UniProt P21450 | A3KMY5 EMBL X57765 | BC133407
InterPro IPR000499 | IPR002175 | IPR000276 GPCRDB ednra_bovin
GENEID 281749
PRINTS PR00570 | PR00366 | PR00237 PFAM PF00001

Details:
NAME ENDOTHELIN RECEPTOR_ET-A_Bos taurus
DESCRIPTION Endothelin-1 receptor precursor (Endothelin A receptor) (ET-A).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE EDNRA
SEQUENCE
METFWLRLSFWVALVGGVISDNPESYSTNLSIHVDSVATFHGTELSFVVTTHQPTNLALP
SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
SLALGDLIYVVIDLPINVFKLLAGRWPFEQNDFGVFLCKLFPFLQKSSVGITVLNLCALS
VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYKGAQHRTCM
LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDTNRCELLSFLLLMDYIGINLATM
NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHEQNNHNTERS
SHKDSIN
FRAGMENT NO

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Scaffold:
TYPE beta-arrestin-1 - 2 REFERENCES 11546805

Coupling with G-proteins:
Family:Gq/11 REFERENCES:1849646
1GPR0027Galpha-11-Bos taurus
Family:Gs REFERENCES:1849646
2GPR0114Galpha-s-Bos taurus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory