gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0814 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ENDOTHELIN RECEPTOR
SUBFAMILY ET-A

Cross References:
UniProt P25101 | O43441 | Q16432 | Q16433 | Q8TBH2 EMBL S63938 | S67127 | X61950 | D90348 | S57498 | L06622 | D11151 | S45956 | S81539 | S81542 | S81545 | AY275462 | AY422989 | BC022511 | S55772 | AF014826
InterPro IPR000499 | IPR002175 | IPR000276 GPCRDB ednra_human
GENEID 1909 MIM 131243
PRINTS PR00570 | PR00366 | PR00237 PFAM PF00001

Details:
NAME ENDOTHELIN RECEPTOR_ET-A_Homo sapiens
DESCRIPTION Endothelin-1 receptor precursor (Endothelin A receptor) (ET-A) (hET-AR) (ETA-R).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE EDNRA | ETA | ETRA
SEQUENCE
METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLP
SNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
VDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCM
LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATM
NSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRS
SHKDSMN
FRAGMENT NO

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Scaffold:
TYPE beta-arrestin-1 - 2 REFERENCES 11546805

Coupling with G-proteins:
Family:G12/13 REFERENCES:10364236
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gq/11 REFERENCES:1849646
3GPR0002Galpha-q-Homo sapiens-2
4GPR0029Galpha-11-Homo sapiens
5GPR0237Galpha-q-Homo sapiens-1
Family:Gs REFERENCES:1849646
6GPR0119Galpha-s-Homo sapiens-2
7GPR0263Galpha-s-Homo sapiens-4
8GPR0266Galpha-s-Homo sapiens-5
9GPR0267Galpha-s-Homo sapiens-6
10GPR0277Galpha-s-Homo sapiens-7
11GPR0278Galpha-s-Homo sapiens
12GPR0395Galpha-s-Homo sapiens-3


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory