gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0737 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY CHOLECYSTOKININ AND GASTRIN RECEPTOR
SUBFAMILY CCK1

Cross References:
UniProt P32238 EMBL L13605 | L19315 | U23430 | U23427 | U23428 | U23429 | D85606 | AY322549 | BC074987
InterPro IPR009126 | IPR000596 | IPR015276 | IPR000276 PDB 1D6G | 1HZN | 1PB2 GPCRDB cckar_human
GENEID 886 MIM 118444
PRINTS PR01822 | PR00524 | PR00237 PFAM PF00001 | PF09193

Details:
NAME CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK1_Homo sapiens
DESCRIPTION Cholecystokinin receptor type A (CCK-A receptor) (CCK-AR)(Cholecystokinin-1 receptor) (CCK1-R).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CCKAR | CCKRA
SEQUENCE 
MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNS
SAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSY
TSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSH
MSASVPPQ
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:12853286
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gq/11 REFERENCES:8503909
3GPR0002Galpha-q-Homo sapiens-2
4GPR0029Galpha-11-Homo sapiens
5GPR0237Galpha-q-Homo sapiens-1
Family:Gs REFERENCES:8503909
6GPR0119Galpha-s-Homo sapiens-2
7GPR0263Galpha-s-Homo sapiens-4
8GPR0266Galpha-s-Homo sapiens-5
9GPR0267Galpha-s-Homo sapiens-6
10GPR0277Galpha-s-Homo sapiens-7
11GPR0278Galpha-s-Homo sapiens
12GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory