gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2796 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY MELANIN-CONCENTRATING HORMONE RECEPTOR
SUBFAMILY MCHR1

Cross References:
UniProt Q8JZL2 EMBL CAAA01177985 | AY049011 | AF498247 | AF498248 | BY276741
InterPro IPR000276 | IPR004047 | IPR008361 GPCRDB mchr1_mouse
GENEID 207911
PRINTS PR00237 | PR01507 | PR01783 PFAM PF00001

Details:
NAME MELANIN-CONCENTRATING HORMONE RECEPTOR_MCHR1_Mus musculus
DESCRIPTION Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Somatostatin receptor-like protein) (SLC-1).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Mchr1 | Gpr24 | Slc1
SEQUENCE 
MSVGAGKEGVGRAVGLRGSRGCQAVEEDPFLDCGAQAPGQGGGGRWRLPQPAWVDGRALH
SREQATCTGCMDLQASLLSTGPNASNISDGQDNFTLAGPPPRTRSVSYINIIMPSVFGTI
CLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWH
FGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSMATLVICLLWAL
SFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVK
ILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFV
YLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTES
KGT
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:10559938
1GPR0021Galpha-o1-Mus musculus
2GPR0227Galpha-i2-Mus musculus-2
3GPR0289Galpha-i1-Mus musculus
4GPR0331Galpha-i2-Mus musculus-1
5GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:10559938
6GPR0031Galpha-11-Mus musculus-2
7GPR0240Galpha-q-Mus musculus
8GPR0360Galpha-11-Mus musculus-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory