gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2739 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY FRIZZLED
SUBFAMILY Frizzled-2

Cross References:
UniProt Q9JIP6 | Q810M0 | Q9JIP5 | Q9WUJ2 EMBL AF206321 | AF206322 | BC049774 | BC055727 | AF139183
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB fzd2_mouse
GENEID 57265
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME FRIZZLED_Frizzled-2_Mus musculus
DESCRIPTION Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Fzd2 | Fzd10
SEQUENCE 
MRARSALPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQT
IMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICE
RARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPSGLQPG
AGGTPGGPGGGGSPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMF
FSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYI
AGFVLQERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLA
AGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGF
VLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATI
VIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITS
GFWIWSGKTLHSWRKFYTRLTNSRHGETTV
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:11563835
1GPR0031Galpha-11-Mus musculus-2
2GPR0240Galpha-q-Mus musculus
3GPR0360Galpha-11-Mus musculus-1
Family:Gi/o REFERENCES:11563835
4GPR0248Galpha-t1-Mus musculus
5GPR0251Galpha-t2-Mus musculus-2
6GPR0320Galpha-t2-Mus musculus-1
7GPR0381Galpha-t-Mus musculus

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory