gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::G-protein View
Entry 1 of 1 :: GPR0248 ::
CLASS Galpha
FAMILY Gi/o
SUBFAMILY Galpha-t
TYPE Galpha-t1

Cross References:
UniProt P20612 | Q80X34 EMBL M25513 | M25506 | M25507 | M25508 | M25509 | M25510 | M25511 | M25512 | BC022793 | BC051412 | BC058810 | U38504
InterPro IPR001019 | IPR001408 | IPR011025
PRODOM PD000281
GENEID 14685
PRINTS PR00318 | PR00441 PFAM PF00503

Details:
NAME Galpha-t1-Mus musculus
DESCRIPTION Guanine nucleotide-binding protein G(t) subunit alpha-1 (Transducinalpha-1 chain).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
POST TRANSLATION MODIFICATIONS null GENE Gnat1 | Gnat-1
SEQUENCE
MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLE
ECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMS
DIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGI
IETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMH
ESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYDGPNTYEDAGNYIK
VQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0495Phosphodiesterase-6-Mus musculus-1Stimulation15251227 | 15988071 | 14699118
2EFF0496Phosphodiesterase-6-Mus musculus-10Stimulation15251227 | 15988071 | 14699118
3EFF0497Phosphodiesterase-6-Mus musculus-11Stimulation15251227 | 15988071 | 14699118
4EFF0498Phosphodiesterase-6-Mus musculus-12Stimulation15251227 | 15988071 | 14699118
5EFF0499Phosphodiesterase-6-Mus musculus-13Stimulation15251227 | 15988071 | 14699118
6EFF0500Phosphodiesterase-6-Mus musculus-14Stimulation15251227 | 15988071 | 14699118
7EFF0501Phosphodiesterase-6-Mus musculus-15Stimulation15251227 | 15988071 | 14699118
8EFF0502Phosphodiesterase-6-Mus musculus-2Stimulation15251227 | 15988071 | 14699118
9EFF0503Phosphodiesterase-6-Mus musculus-3Stimulation15251227 | 15988071 | 14699118
10EFF0504Phosphodiesterase-6-Mus musculus-4Stimulation15251227 | 15988071 | 14699118
11EFF0505Phosphodiesterase-6-Mus musculus-5Stimulation15251227 | 15988071 | 14699118
12EFF0506Phosphodiesterase-6-Mus musculus-6Stimulation15251227 | 15988071 | 14699118
13EFF0507Phosphodiesterase-6-Mus musculus-7Stimulation15251227 | 15988071 | 14699118
14EFF0508Phosphodiesterase-6-Mus musculus-8Stimulation15251227 | 15988071 | 14699118
15EFF0509Phosphodiesterase-6-Mus musculus-9Stimulation15251227 | 15988071 | 14699118

Coupling with GPCRs:
1GPCR1935OPSIN/RHODOPSIN FAMILY_Blue opsin_Mus musculus3867351
2GPCR2739FRIZZLED_Frizzled-2_Mus musculus11563835
3GPCR1965OPSIN/RHODOPSIN FAMILY_Green-sensitive opsin_Mus musculus3867351
4GPCR2009OPSIN/RHODOPSIN FAMILY_Opsin 3_Mus musculus3867351
5GPCR2011OPSIN/RHODOPSIN FAMILY_Opsin 4_Mus musculus3867351
6GPCR2105OPSIN/RHODOPSIN FAMILY_Rhodopsin_Mus musculus3867351
7GPCR2349OPSIN/RHODOPSIN FAMILY_Visual pigment-like peropsin_Mus musculus3867351




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athina University of Athens
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Laboratory