gpDB: a database of G-proteins and their interaction with GPCRs
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2621 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR
SUBFAMILY PAC1

Cross References:
UniProt P41586 EMBL D17516 | AB065700 | AY366498 | U09216
InterPro IPR001879 | IPR002285 | IPR000832 PDB 2JOD GPCRDB pacr_human
GENEID 117 MIM 102981
PRINTS PR00249 | PR01156 PFAM PF00002 | PF02793

Details:
NAME VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_PAC1_Homo sapiens
DESCRIPTION Pituitary adenylate cyclase-activating polypeptide type I receptorprecursor (PACAP type I receptor) (PACAP-R-1).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ADCYAP1R1
SEQUENCE
MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIP
LFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKV
NRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:8396727
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1
Family:Gs REFERENCES:8396727
4GPR0119Galpha-s-Homo sapiens-2
5GPR0263Galpha-s-Homo sapiens-4
6GPR0266Galpha-s-Homo sapiens-5
7GPR0267Galpha-s-Homo sapiens-6
8GPR0277Galpha-s-Homo sapiens-7
9GPR0278Galpha-s-Homo sapiens
10GPR0395Galpha-s-Homo sapiens-3


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory